Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Tumour Mutational Burden and Immune Checkpoint Inhibitor Response in Non-small Cell Lung Cancer: A Continuous Modelling Approach.
Target Oncol
January 2025
College of Medicine and Public Health, Flinders University, Adelaide, SA, Australia.
Background: Tumour mutational burden (TMB) is an established biomarker for patients treated with immune checkpoint inhibitors (ICIs). The optimal TMB cut-off is uncertain. It is also uncertain whether there is a sharp TMB threshold or a more graduated change in clinical outcomes as TMB increases.
View Article and Find Full Text PDFLocal flap guidance for scalp reconstruction following Mohs micrographic surgery.
Arch Dermatol Res
January 2025
Department of Dermatology, University of Texas Medical Branch, 301 University Boulevard, 4.112, McCullough Building, Galveston, TX, 77555, USA.
Keratinocyte carcinomas (KCs) are commonly located on the scalp and often treated with excision with peripheral and deep en face margin assessment (PDEMA), with Mohs micrographic surgery (MMS) being the most frequently used method. Resection of these malignancies results in wounds with a wide variety of sizes, ranging from small, sub-centimeter defects, to extensive, nearly complete scalp defects. MMS is often the preferred treatment for tumor resection and margin clearance, as it allows for maximal healthy tissue preservation and has the lowest recurrence rates.
View Article and Find Full Text PDFSoft tissue tumor imaging in adults: European Society of Musculoskeletal Radiology-Guidelines 2024: imaging immediately after neoadjuvant therapy in soft tissue sarcoma, soft tissue tumor surveillance, and the role of interventional radiology.
Eur Radiol
December 2024
Department of Radiology AZ Sint Maarten Mechelen, University (Hospital) Antwerp, Antwerp, Belgium.
Article Synopsis
- The ESSR updated its 2015 consensus on soft tissue tumor imaging due to advancements in technology and updated classifications.
- A panel of 46 radiologists from 12 European countries used a validated Delphi method to reach consensus on imaging strategies, resulting in high agreement on 47 statements.
- Key findings highlight that MRI is preferred for monitoring soft tissue sarcomas, with chest CT recommended for assessing metastasis and interventional radiology playing a role in treating specific cases.
Radiological, clinical, and molecular analyses reveal distinct subtypes of butterfly glioblastomas affecting the prognosis.
Neurooncol Adv
October 2024
Department of Neurosurgery, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan.
Article Synopsis
- Glioblastoma (GB) is highly invasive, and the study investigates the origins and molecular characteristics of butterfly glioblastoma (bGB) by analyzing a cohort of 34 bGB patients alongside others from public datasets.
- The results show that bGB can arise from two distinct origins—corpus callosum (CC) and cerebral hemisphere—with unique molecular mutations and prognostic implications, particularly identifying the CC-type as having worse survival outcomes.
- The study emphasizes the need for further research to understand the clinical significance and differences between the identified bGB subtypes to enhance treatment strategies and patient care.
Management of Clinically Negative Neck in Early-Stage (T1-2N0) Oral Squamous-Cell Carcinoma (OSCC): Ten Years of a Single Institution's Experience.
J Clin Med
November 2024
Department of Odontostomatological and Maxillofacial Sciences, La Sapienza University of Rome, 00185 Rome, Italy.
: Oral cavity squamous-cell carcinoma is among the most frequent head and neck neoplasms. Early-stage T1/T2N0 accounts for 40/45% of new diagnoses. Of these, about 30% of cases hide occult metastases in the neck.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!