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[Statin for the prevention and treatment of hepatocellular carcinoma: use or wait?].
Zhonghua Gan Zang Bing Za Zhi
January 2025
The First Clinical Medical College of Lanzhou University, Lanzhou730000, China Department of Hepatology & Infectious Diseases, the First Hospital of Lanzhou University, Lanzhou, 730000, China Institute of Portal Hypertension, the First Hospital of Lanzhou University, Lanzhou730000, China.
Hepatocellular carcinoma (HCC) is a kind of malignant tumor with an extremely high morbidity and mortality incidence rate. Although some new progress has been made in recent treatment, the overall prognosis is still poor. Therefore, the prevention and treatment of HCC have important clinical significance.
View Article and Find Full Text PDF[The effects of environmental stressors on cardiovascular health].
Inn Med (Heidelb)
December 2024
Zentrum für Kardiologie, Universitätsmedizin Mainz, Johannes Gutenberg-Universität, Langenbeckstraße 1, 55131, Mainz, Deutschland.
Noncommunicable diseases (NCDs) are responsible for the premature deaths of more than 38 million people each year, making them the leading cause of the global burden of disease, accounting for 70% of global mortality. The majority of these deaths are caused by cardiovascular diseases. The risk of NCDs is closely related to exposure to environmental stressors such as air pollution, noise pollution, artificial light at night, and climate change, including extreme heat, sandstorms, and wildfires.
View Article and Find Full Text PDFExtreme LDL-C concentration is associated with increased cardiovascular disease in women with homozygous familial hypercholesterolemia.
J Clin Lipidol
November 2024
Lipids, Nutrition, and Cardiovascular Prevention Clinic of the Montreal Clinical Research Institute, Montreal, Québec, Canada; Department of Medicine, Divisions of Experimental Medicine and Medical Biochemistry, McGill University, Montreal, Québec H3G 2M1, Canada. Electronic address:
Background: Homozygous familial hypercholesterolemia (HoFH) is a rare genetic disease of low-density lipoprotein cholesterol (LDL-C) metabolism. Despite the devastating effect of this disease on atherosclerotic cardiovascular health, the disease phenotype and severity are more heterogeneous than previously thought. The predictors of atherosclerotic cardiovascular disease (ASCVD) in HoFH patients have never been systematically studied.
View Article and Find Full Text PDFEfficacy of Low-Density Lipoprotein Cholesterol Apheresis in the Treatment of Familial Hypercholesterolemia: Single Center Experience.
Exp Clin Endocrinol Diabetes
December 2024
Department of Internal Medicine, Division of Endocrinology and Metabolism, Istanbul University Istanbul Faculty of Medicine, Istanbul, Turkey.
Purpose: Familial hypercholesterolemia (FH) is a genetic disorder associated with extremely high levels of low-density lipoprotein cholesterol (LDL-C) and increased incidence of cardiovascular disease. We aimed to evaluate the efficacy and long-term outcomes of lipoprotein apheresis (LA) in the treatment of FH.
Methods: Cardiovascular events that occurred before and after LA treatment were evaluated by reviewing previous medical records of patients with FH.
Extremely rare coronary anomaly as cause of palpitations: a case report of single right coronary artery-multimodality imaging and its impact on treatment decisions.
Eur Heart J Case Rep
November 2024
Department of Cardiology and Electrotherapy, Faculty of Medical Sciences in Zabrze, Silesian Center for Heart Diseases, Medical University of Silesia, ul. Marii Curie Skłodowskiej 9, 41-800 Zabrze, Poland.
Background: We report the case of a 63-year-old white Caucasian male patient admitted to the clinic because of atypical angina and palpitations. Other comorbidities included hypertension, hyperuricaemia, and hypercholesterolaemia. He was admitted to a tertiary cardiac centre for deepened diagnostics of his complaints.
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