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Akkermansia muciniphila Mediated the Preventive Effect of Disulfiram on Acute Liver Injury via PI3K/Akt Pathway.
Microb Biotechnol
January 2025
Huadong Medical Institute of Biotechniques, Nanjing, China.
Acetaminophen induced acute liver injury (ALI) has a high incidence and is a serious medical problem, but there is a lack of effective treatment. The enterohepatic axis is one of the targets of recent attention due to its important role in liver diseases. Disulfiram (DSF) is a multitarget drug that has been proven to play a role in a variety of liver diseases and can affect intestinal flora, but whether it can alleviate ALI is not clear.
View Article and Find Full Text PDFChanges in the potato rhizosphere microbiota richness and diversity occur in a growth stage-dependent manner.
Sci Rep
January 2025
Department of Agricultural Biotechnology, Seoul National University, Seoul, 08826, Republic of Korea.
Plant root and soil-associated microbiomes are influenced by niches, including bulk and rhizosphere soil. In this work, we collected bulk and rhizosphere soil samples at four potato developmental stages (leaf growth, flowering, tuber elongation and harvest) to identify whether rhizosphere microbiota are structured in a growth stage-dependent manner. The bacterial and fungal microbiota showed significant temporal differences in the rhizosphere and bulk soil.
View Article and Find Full Text PDFEffects of replacing soybean meal with cottonseed meal on growth performance, carcass trait, intestinal development and intestinal microbiota of broiler chickens.
Poult Sci
December 2024
New Hope Liuhe Co., Ltd., Quality Control for Feed and Products of Livestock and Poultry Key Laboratory of Sichuan Province, Chengdu, China; Weifang Newhope LiuHe Feed Technology Co. Ltd., Weifang, China. Electronic address:
This experiment was conducted to evaluate the effects of replacing soybean meal (SBM) with cottonseed meal (CSM) on growth performance, carcass trait, intestinal development and intestinal microbiota of broilers. A total of 792 one-day-old male Ross 308 broiler chickens were randomly allotted to three treatment groups, with 8 replicates per group and 33 birds per replicate. The control birds were administered a diet consisting primarily of corn and soybean meal.
View Article and Find Full Text PDFInduced Resistance of Ocular Surface Flora in Patients Undergoing Cataract Surgery.
S D Med
October 2024
University of South Dakota Sanford School of Medicine, Sioux Falls, South Dakota.
Purpose: This study investigated the effects of pre-operative topical moxifloxacin prior to cataract surgery on the growth of ocular surface bacteria and induced antibiotic resistance after a 3-day course of moxifloxacin.
Methods: The study was a prospective, dual arm, randomized study. The study group of 17 patients used moxifloxacin four times daily, for three days prior to surgery.
The characteristics of intestinal flora of Tibetan sheep in different regions at high altitude were revealed based on metagenomic technique.
Heliyon
July 2024
College of Agriculture and Animal Husbandry, Qinghai University, Xining, Qinghai, 810016, China.
Tibetan sheep play a vital role in the livelihoods of herders and are an important part of the ecosystem of the Tibetan Plateau. In order to study the characteristics of the gut microorganisms of Tibetan sheep at high altitude, this study employed macrogenomic techniques to analyse the diversity and differences in the gut flora of Tibetan sheep in different regions of high altitude and high cold. The results demonstrated that at the phylum level, the dominant phylum in the ileo-cecum segment of Tibetan sheep in Qilian, Henan and Gonghe counties was identical, namely , and .
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