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Photothermal spectroscopy on-chip sensor for the measurement of a PMMA film using a silicon nitride micro-ring resonator and an external cavity quantum cascade laser.
Nanophotonics
May 2024
Centre for Advanced Photonics and Process Analysis, Munster Technological University, T12 T66T Bishopstown, Cork, Ireland.
Article Synopsis
- - Laser-based mid-IR photothermal spectroscopy (PTS) is a rapid and sensitive analytical method that utilizes advanced laser technology to capture the absorption characteristics of various materials, such as liquids or solids.
- - This study utilizes an external cavity quantum cascade laser (EC-QCL) to analyze a thin film of polymethyl methacrylate (PMMA) on a silicon nitride micro-ring resonator, demonstrating its effectiveness in creating an on-chip photothermal sensor.
- - The research highlights the optimal alignment and focusing techniques for the laser setup, showing that PTS can lead to compact, efficient sensors suitable for real-time monitoring in industrial applications.
Raman spectroscopy - a visit to the literature on plant, food, and agricultural studies.
J Sci Food Agric
August 2024
Instituto de Ciências Agrárias (ICIAG), Universidade Federal de Uberlândia (UFU), Uberlândia, Brazil.
Raman spectroscopy, a fast, non-invasive, and label-free optical technique, has significantly advanced plant and food studies and precision agriculture by providing detailed molecular insights into biological tissues. Utilizing the Raman scattering effect generates unique spectral fingerprints that comprehensively analyze tissue composition, concentration, and molecular structure. These fingerprints are obtained without chemical additives or extensive sample preparation, making Raman spectroscopy particularly suitable for in-field applications.
View Article and Find Full Text PDFComment on "Raman spectroscopy combined with multivariate statistical algorithms for the simultaneous screening of cervical and breast cancers".
Lasers Med Sci
July 2024
Laser and Biotechnical Systems Department, Samara National Research University, Moskovskoe shosse 34, Samara, 443086, Russia.
This article discusses current research on the detection of cervical and breast cancer using in vitro Raman spectral analysis of human serum by Cao et al. (2024) which was published in the Lasers in Medical Science journal. Despite the high accuracy of the suggested approach (93%), the demonstrated findings could be treated unclear due to possible overestimation of the classification models.
View Article and Find Full Text PDFImportance: Despite widespread availability and consensus on its advantages for detailed imaging of geographic atrophy (GA), spectral-domain optical coherence tomography (SD-OCT) might benefit from automated quantitative OCT analyses in GA diagnosis, monitoring, and reporting of its landmark clinical trials.
Objective: To analyze the association between pegcetacoplan and consensus GA SD-OCT end points.
Design, Setting, And Participants: This was a post hoc analysis of 11 614 SD-OCT volumes from 936 of the 1258 participants in 2 parallel phase 3 studies, the Study to Compare the Efficacy and Safety of Intravitreal APL-2 Therapy With Sham Injections in Patients With Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (OAKS) and Study to Compare the Efficacy and Safety of Intravitreal APL-2 Therapy With Sham Injections in Patients With Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (DERBY).
Decidual leukocytes respond to African lineage Zika virus infection with mild anti-inflammatory changes during acute infection in rhesus macaques.
Front Immunol
March 2024
Department of Comparative Biosciences, University of Wisconsin-Madison, Madison, WI, United States.
Zika virus (ZIKV) can be vertically transmitted during pregnancy resulting in a range of adverse pregnancy outcomes. The decidua is commonly found to be infected by ZIKV, yet the acute immune response to infection remains understudied . We hypothesized that African-lineage ZIKV infection induces a pro-inflammatory response in the decidua.
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