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Objectives: The number of elderly people with stomach cancer is increasing; therefore, minimally invasive surgical treatments are required. Elderly patients have multiple comorbidities and are prone to postoperative weight loss, nutritional disorders, Postgastrectomy syndrome (PGS), and decreased quality of life (QOL). Total gastrectomy is particularly associated with these complications, although aboral-pouch creation reportedly improves the condition by compensating for lost reservoir capacity.

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It is well established that the preoperative nutritional status of gastric cancer (GC) patients significantly affects the prognosis of the operated patients, their overall survival, as well as the disease-specific survival. Existing data support that preoperative assessment of nutritional status and early correction of nutritional deficiencies exert a favorable effect on early postoperative outcomes. A variety of relevant indices are used to assess the nutritional status of GC patients who are candidates for surgery.

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Uncut Roux-en-Y reconstruction after distal gastrectomy for gastric cancer.

Cochrane Database Syst Rev

February 2024

Department of General Surgery, West China Hospital, Sichuan University, Chengdu, China.

Background: Choosing an optimal reconstruction method is pivotal for patients with gastric cancer undergoing distal gastrectomy. The uncut Roux-en-Y reconstruction, a variant of the conventional Roux-en-Y approach (or variant of the Billroth II reconstruction), employs uncut devices to occlude the afferent loop of the jejunum. This modification is designed to mitigate postgastrectomy syndrome and enhance long-term functional outcomes.

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Segmental gastrectomy, mini-distal gastrectomy and local resection of the stomach are function-preserving curative gastrectomies (FPGs), which are used to treat gastric cancer in specialized centers. These surgical options are less invasive and can alleviate postgastrectomy symptoms more than standard gastrectomy; however, their association with prognosis remains to be fully elucidated. The present study aimed to compare the survival prognosis of patients diagnosed as node-negative by sentinel node biopsy (SNB) treated via FPG with reduced lymph node dissection with that of patients who underwent guideline gastrectomy (GL).

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Article Synopsis
  • A study assessed the impact of a daily elemental diet (ED) on skeletal muscle mass loss in gastric cancer patients after surgery, following previous findings that it reduced body weight loss postoperatively.
  • The analysis utilized data from patients undergoing total or distal gastrectomy and compared changes in skeletal muscle mass index (%SMI) between those on the ED and control groups one year later.
  • Results showed that while the ED group had a lower median %SMI loss than the control group, the difference was not statistically significant, indicating no clear benefit of the diet in preventing muscle loss post-gastrectomy.
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