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Chest pain after elective percutaneous coronary intervention as trigger of takotsubo syndrome-a case report.
Eur Heart J Case Rep
January 2025
Fondazione Toscana Gabriele Monasterio, Via Giuseppe Moruzzi 1, 56124 Pisa, Italy.
Background: Takotsubo syndrome (TTS) is characterized by transient left ventricular dysfunction, often triggered by emotional or physical stress. It usually presents with clinical features similar to acute coronary syndrome, making its occurrence following elective percutaneous coronary intervention (PCI) challenging to diagnose and treat.
Case Summary: A 67-year-old man with ischaemic heart disease and recurrent angina underwent elective PCI of the right coronary artery.
Triggering Pyroptosis by Doxorubicin-Loaded Multifunctional Nanoparticles in Combination with Decitabine for Breast Cancer Chemoimmunotherapy.
ACS Appl Mater Interfaces
October 2024
College of Pharmacy, Xinxiang Medical University, Xinxiang 453003, P. R. China.
Pyroptosis, a form of programmed cell death, holds great promise for breast cancer treatment. However, the downregulation of gasdermin E (GSDME) limits the effectiveness of pyroptosis. To address this challenge, we developed a folic acid-modified and glutathione/reactive oxygen species dual-responsive nanocarrier (FPSD NPs) for the targeted delivery of doxorubicin (DOX).
View Article and Find Full Text PDFFast resolution of mild midvetricular takotsubo syndrome triggered by blunt chest trauma: case study.
Pol Merkur Lekarski
July 2024
DEPARTMENT OF INTERNAL MEDICINE, JÓZEF STRUŚ HOSPITAL, POZNAŃ, POLAND.
Blunt chest trauma (BCT) may rarely trigger stress-induced takotsubo syndrome (TTS) which requires dif f erential diagnosis with myocardial contusion and BCT-induced myocardial infarction. So far reported cases have been presented as apical ballooning or inverted (reverse) TTS forms but not as a midventricular variant. The authors described a case of a 53-year-old female admitted to Intensive Care Unit after motor vehicle accident with BCT and airbag deployment during car roll over.
View Article and Find Full Text PDFΤakotsubo Syndrome After Surgical Removal of the Thyroid Gland and Major Bleeding.
Cureus
April 2024
Cardiology, Aristotle University of Thessaloniki, AHEPA University Hospital, Thessaloniki, GRC.
A 58-year-old male with a medical history of arterial hypertension, dyslipidemia, and psoriasis was admitted for a scheduled surgical removal of the thyroid gland. During the surgery, the patient suffered severe blood loss caused by vascular complications. After the operation, his electrocardiogram showed diffuse ST segment elevation along with high-sensitivity cardiac troponin T elevation and severe left ventricular systolic dysfunction.
View Article and Find Full Text PDFDirect degradation and stabilization of proteins: New horizons in treatment of nonalcoholic steatohepatitis.
Biochem Pharmacol
February 2024
School of Kinesiology, Shanghai University of Sport, Shanghai 200438, PR China.
Nonalcoholic fatty liver disease (NAFLD) is featured with excessive hepatic lipid accumulation and its global prevalence is soaring. Nonalcoholic steatohepatitis (NASH), the severe systemic inflammatory subtype of NAFLD, is tightly associated with metabolic comorbidities, and the hepatocytes manifest severe inflammation and ballooning. Currently the therapeutic options for treating NASH are limited.
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