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Exploring salinity induced adaptations in marine diatoms using advanced photonic techniques.
Sci Rep
December 2024
Center for Photonic Science and Engineering, Skolkovo Institute of Science and Technology, 30 Bolshoy Boulevard, bld. 1, Moscow, 121205, Russia.
Photonic-based methods are crucial in biology and medicine due to their non-invasive nature, allowing remote measurements without affecting biological specimens. The study of diatoms using advanced photonic methods remains a relatively underexplored area, presenting significant opportunities for pioneering discoveries. This research provides a comprehensive analysis of marine diatoms, specifically Nitzschia sp.
View Article and Find Full Text PDFImaging pathology in archived cornea with Fuchs' endothelial corneal dystrophy including tissue reprocessing for volume electron microscopy.
Sci Rep
December 2024
Structural Biophysics Research Group, School of Optometry & Vision Sciences, Cardiff University, Cardiff, Wales, UK.
Fuchs' endothelial corneal dystrophy (FECD) is a common sight-threatening condition characterised by pathological changes in the posterior cornea. Here we report observations by light, transmission and volume scanning electron microscopy on changes in the endothelium and matrix associated with the characteristic deformations of Descemet's membrane, termed guttae. Specimens were archived full-thickness human corneal tissue, removed during graft surgery, that had been fixed, stained and embedded by conventional processing methods for examination by transmission electron microscopy more than 40-years previously.
View Article and Find Full Text PDFPhase-transition-induced dynamic surface wrinkle pattern on gradient photo-crosslinking liquid crystal elastomer.
Nat Commun
December 2024
School of Materials Science and Engineering, East China University of Science and Technology, Shanghai, China.
Liquid crystal elastomers (LCEs) with various deformation properties based on phase transition were widely used as actuators and provided potential to fabricate functional surfaces with tunable microstructure. Herein, we demonstrate a strategy to fabricate dynamic micro wrinkles on LCE surfaces based on LC phase transition. Stable micron-sized surface wrinkles on the anthracene-containing LCE film (AnLCE) are fabricated by ultraviolet exposure induced gradient cross-linking and subsequently stretching-releasing (UV-SR).
View Article and Find Full Text PDFCorrelation between conventional karyotype, interphase FISH and immunophenotype in risk stratification of newly diagnosed plasma cell myeloma: An observational study.
Med J Armed Forces India
December 2024
Professor (Lab Sciences & Molecular Medicine), Army Hospital (R&R), Delhi Cantt, India.
Background: Plasma cell myeloma (PCM) is a common adult hematological neoplasm of terminally differentiated B-cells resulting in accumulation of monoclonal plasma cells. PCM is heterogeneous disease with survival time varies from months to years, determined by age, stage, cytogenetics abnormalities, and treatment response. There is conflicting evidence in role of immunophenotype as a prognostic indicator.
View Article and Find Full Text PDFCholesterol mediates the potential adverse influence of graphene quantum dots on placental lipid membrane model.
Sci Rep
December 2024
College of Physical Science and Technology, Yangzhou University, Yangzhou, 225009, Jiangsu, China.
Nanomaterial-biomembrane interactions constitute a critical biological process in assessing the toxicity of such materials in theoretical studies. However, many investigations simplify these interactions by using membrane models containing only one or a few lipid types, deviating significantly from the complexity of real membrane compositions. In particular, cholesterol, a ubiquitous lipid essential for regulating membrane fluidity and closely linked to various diseases, is often overlooked.
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