Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1103/PhysRevLett.55.795 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Saponins Effect on Human Insulin Amyloid Aggregation.
Biomolecules
December 2024
Department of Life and Environmental Sciences, Marche Polytechnic University, I-60131 Ancona, Italy.
The misfolding and amyloid aggregation of proteins have been attracting scientific interest for a few decades, due to their link with several diseases, particularly neurodegenerative diseases. Proteins can assemble and result in insoluble aggregates that, together with intermediate oligomeric species, modify the extracellular environment. Many efforts have been and are devoted to the search for cosolvents and cosolutes able to interfere with amyloid aggregation.
View Article and Find Full Text PDFRoles of human papillomavirus in cancers: oncogenic mechanisms and clinical use.
Signal Transduct Target Ther
January 2025
Department of Biotherapy, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China.
Human papillomaviruses, particularly high-risk human papillomaviruses, have been universally considered to be associated with the oncogenesis and progression of various cancers. The genome of human papillomaviruses is circular, double-stranded DNA that encodes early and late proteins. Each of the proteins is of crucial significance in infecting the epithelium of host cells persistently and supporting viral genome integrating into host cells.
View Article and Find Full Text PDFExploring RNA-Seq Data Analysis Through Visualization Techniques and Tools: A Systematic Review of Opportunities and Limitations for Clinical Applications.
Bioengineering (Basel)
January 2025
Department of Computer Science and Data Science, School of Applied Computational Sciences, Meharry Medical College, Nashville, TN 37208, USA.
RNA sequencing (RNA-seq) has emerged as a prominent resource for transcriptomic analysis due to its ability to measure gene expression in a highly sensitive and accurate manner. With the increasing availability of RNA-seq data analysis from clinical studies and patient samples, the development of effective visualization tools for RNA-seq analysis has become increasingly important to help clinicians and biomedical researchers better understand the complex patterns of gene expression associated with health and disease. This review aims to outline the current state-of-the-art data visualization techniques and tools commonly used to frame clinical inferences from RNA-seq data and point out their benefits, applications, and limitations.
View Article and Find Full Text PDFA pupil called Worry: Mydriasis in orbital surgery.
Clin Neurol Neurosurg
January 2025
Department of Ophthalmology, University Hospitals Leuven, Leuven, Belgium; Department of Neurosciences, Catholic University Leuven, Leuven, Belgium. Electronic address:
Objective: Surgeons routinely check the pupils to assess, in part, the brain stem function and the neural integrity of the visual system. Where a relative afferent pupillary defect is difficult to notice during surgery, an efferent pupillary defect or mydriasis is clearly recognizable. Visual loss in orbital surgery is attributed to compromised perfusion of the optic nerve, retina, or choroid, but an association with mydriasis is generally not assumed.
View Article and Find Full Text PDFNon-coding RNAs in urinary bladder cancer microenvironment: Diagnostic, therapeutic, and prognostic perspective.
Pathol Res Pract
January 2025
Department of Pathology, Faculty of Medicine, Suez University, Suez, Egypt.
Urinary bladder cancer (UBC) is the ninth most common cancer worldwide. Despite the reliance of UBC therapy on definite pathological grading and classifications, the clinical response among patients varies widely. The molecular basis of this type of cancer appeals to considerable research; hence, new diagnostic and therapeutic options are introduced.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!