Spontaneous pinealoma in a male Crj:CD (SD) IGS rat.

J Vet Med Sci

Shiraoka Research Station of Biological Science, Nissan Chemical Industries, Ltd., Saitama, Japan.

Published: January 1999

A pinealoma (benign) was found in a 61-week-old male Crj:CD (SD) IGS rat. The neoplasm was located between the cerebral hemispheres and the cerebellum. Histologically, the tumor cells consisted of two cell types: large, pale-staining cells and small dark-staining cells. A fibrovascular stroma divided the tumor cells into incomplete lobules or nest structures. Relatively numerous mitoses were noted in the tumor cells. Ultrastructurally, the tumor cells contained dense-cored vesicles, approximately 120 nm in diameter.

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http://dx.doi.org/10.1292/jvms.61.41DOI Listing

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