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Case report: Treatment of a rare primary cerebellum histiocytic sarcoma with surgery and radiotherapy.
Front Oncol
December 2024
Head and Neck Oncology Ward, West China Hospital of Sichuan University, Chengdu, China.
Background: Histiocytic sarcoma originates in various tissues, including the skin, lymph nodes, gastrointestinal tract, lungs, bone marrow, and central nervous system. Primary central nervous system histiocytic sarcoma (PCNSHS) is exceptionally rare, known for its aggressive behavior and poor prognosis. This report describes a case of PCNSHS in the cerebellum treated with surgery and radiotherapy.
View Article and Find Full Text PDFSystemic Therapy Improvements Will Render Locoregional Treatments Obsolete for Patients with Cancer with Liver Metastases.
Hematol Oncol Clin North Am
February 2025
Department of Medicine, Division of Hematology Oncology, Vanderbilt University Medical Center, 777 Preston Research Building, 2220 Pierce Avenue, Nashville, TN 37232, USA. Electronic address: https://twitter.com/jordanberlin5.
Hepatic metastases are a major cause of morbidity and mortality for patients with cancer. Apart from curative resection, which offers patients the potential for long-term survival, an array of locoregional therapies, with limited evidence of improving survival, are used to treat them. The authors use examples from the realm of gastrointestinal cancer, largely focusing on the experience of patients with neuroendocrine cancer, hepatobiliary cancer, and colorectal cancer, to suggest that current systemic therapies offer, at minimum, similar survival outcomes for patients compared with these locoregional approaches.
View Article and Find Full Text PDFDuodenal obstruction in a 38-year-old: Case report of an unusual ovarian cancer presentation requiring a Whipple procedure.
Heliyon
August 2024
Department of Gynecology with Center for Oncological Surgery, Charité Universitätsmedizin Berlin, Germany.
Since ovarian cancer typically spreads intraperitoneally or via lymphatics, a retroperitoneal duodenal obstruction is a rare presentation of ovarian cancer. Such upper gastrointestinal obstruction in a young patient is diagnostically challenging and surgically difficult to address. In this case report, we describe that in an interdisciplinary approach a Whipple pancreaticoduodenectomy could be safely implemented into the interval debulking surgery to achieve complete cytoreduction.
View Article and Find Full Text PDFManagement of gastrointestinal stromal tumor and acute appendicitis during pregnancy: A case report.
Case Rep Womens Health
October 2024
Department of Anesthesiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.
Gastrointestinal stromal tumors (GISTs) are neoplasms of neural cells in the gastrointestinal tract; they typically develop in older adults, with less than 10% of cases presenting among patients under the age of 40. This report describes the clinical course and management of a 28-year-old woman with a history of irritable bowel syndrome (IBS) who presented with acute upper abdominal pain. Surgical pathology confirmed a diagnosis of metastatic GIST.
View Article and Find Full Text PDFFactors affecting dietary progression post cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC).
Clin Nutr ESPEN
October 2024
School of Medicine, Smart Foods Centre, Illawarra Health and Medical Research Institute, University of Wollongong, Building 32, Northfields Ave, Keiraville, NSW, 2500, Australia.
Article Synopsis
- The study investigates how patients recovering from cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) progress with their diets postoperatively and the factors influencing this progression.* -
- Out of 42 patients, those with fast dietary progression (FDP) started a full fluid diet within 7 days, while the slow dietary progression (SDP) group took longer and faced more complications, such as prolonged ileus and longer hospital stays.* -
- The findings suggest that addressing the dietary progression speed and implementing timely nutritional strategies, such as parenteral nutrition, could improve recovery outcomes for patients with peritoneal carcinomatosis.*
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