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CircDNA2-Educated YTHDF2 Phase Separation Promotes PM-Induced Malignant Transformation Through the Blunting of GADD45A Expression.
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School of Public Health, Capital Medical University, Beijing, 100069, P. R. China.
Substantial epidemiological evidence suggests a significant correlation between particulate matter 2.5 (PM) and lung cancer. However, the mechanism underlying this association needs to be further elucidated.
View Article and Find Full Text PDFReoperations as an Outcome Indicator for Developmental Dysplasia of the Hip Treated at Walking Age.
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Department of Orthopaedic Surgery, Children Hospital, National Taiwan University Hospital, Taipei, Taiwan.
Background: Reoperation is a major adverse event following surgical treatment but has yet to be used as a primary outcome measure in population studies to assess current treatments for developmental dysplasia of the hip (DDH). The purpose of the present study was to explore the risk factors associated with reoperations following procedures under anesthesia ("operations") for DDH in patients between the ages of 1 and 3.00 years, with the goal of deriving treatment recommendations.
View Article and Find Full Text PDFResults of 331 Two-Stage Exchanges for PJI Following THA: Low Reinfection and Mechanical Failure Rates at 10 Years.
J Bone Joint Surg Am
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Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota.
Background: The relative advantages and disadvantages of 2-stage versus 1-stage management of infection following total hip arthroplasty (THA) are the current subject of intense debate. To understand the merits of each approach, detailed information on the short and, importantly, longer-term outcomes of each must be known. The purpose of the present study was to assess the long-term results of 2-stage exchange arthroplasty following THA in one of the largest series to date.
View Article and Find Full Text PDFThe population dynamics of clustered consumer-resource spatial patterns: Insights from the demographics of a Turing mechanism.
Proc Natl Acad Sci U S A
January 2025
Department of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, MI 48104.
In ecology, Alan Turing's proposed activation-inhibition mechanism has been abstracted as corresponding to several ecological interaction types to explain pattern formation in ecosystems. Consumer-resource interactions have strong theoretical arguments linking them to both the Turing mechanism and pattern formation, but there is little empirical support to demonstrate these claims. Here, we connect several lines of evidence to support the proposition that consumer-resource interactions can create empirically observed spatial patterns through a mechanism similar to Turing's theory.
View Article and Find Full Text PDFDecoding ruminative reflection in healthy individuals: The role of triple network connectivity.
Int J Clin Health Psychol
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Key Laboratory of Cognition and Personality, Faculty of Psychology, Southwest University, Chongqing, China.
Ruminative reflection has been linked to enhanced executive control in processing internally represented emotional information, suggesting it may serve as an adaptive strategy for emotion regulation. Investigating the neural substrates of reflection can deepen our understanding of its adaptive properties. This study used network-based statistic (NBS)-Predict methodology to identify resting state functional connectivity (FC)-based predictors of ruminative reflection in a healthy sample.
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