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Integrating proteomics and metabolomics to evaluate impact of semen collection techniques on the quality and cryotolerance of goat semen.
Sci Rep
November 2024
Yunnan Animal Science and Veterinary Institute, Jindian, Panlong District, Kunming, 650224, China.
Results of artificial insemination (AI) are affected by changes in sperm quality and the function throughout collection and preservation procedures. Proteome and metabolome alterations of sperm treated with the different procedures in goat, however, aren't fully understood. To this end, we sought to investigate the impacts of rectal probe electrostimulation (EE) and artificial vagina (AV) semen collection methods on the quality and the cryotolerance of goat sperm, with additional focus on proteomic and metabolomic analyses.
View Article and Find Full Text PDFContext: Despite efforts to enhance equity, disparities in early palliative care (PC) access for historically minoritized patients with advanced breast cancer (ABC) persist. Insight into patient and clinician perspectives are needed to inform future models aimed at improving equity in PC access and outcomes.
Objectives: To explore qualitative barriers and facilitators to early PC access in an urban setting with Black and Latina women with ABC.
Understanding Health Outcomes in Pediatric Inflammatory Bowel Diseases: Contributing Factors that Aren't so Black and White.
J Pediatr
February 2024
Division of Gastroenterology, Hepatology, and Nutrition, Boston Children's Hospital, Boston, Massachusetts.
Ashwagandha- Withania somnifera (L.) Dunal as a multipotent neuroprotective remedy for genetically induced motor dysfunction and cellular toxicity in human neurodegenerative disease models of Drosophila.
J Ethnopharmacol
January 2024
Developmental Genetics Laboratory, Department of Studies in Zoology, University of Mysore, Mysuru, 570006, India. Electronic address:
Ethnopharmacological Relevance: Ashwagandha-Withania somnifera (L.) Dunal, well known for its multipotent therapeutic properties has been used in Ayurveda for 3000 years. The plant with more than 50 active phytoconstituents is recognised for its anti-cancerous, anti-diabetic, anti-inflammatory, anti-microbial, and neurotherapeutic properties demonstrated in in vitro studies and chemically induced rodent models.
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