Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1103/physrevd.40.2903 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Resveratrol reduces RVLM neuron activity via activating the AMPK/Sirt3 pathway in stress-induced hypertension.
J Biol Chem
March 2025
School of Environmental and Chemical Engineering, Shanghai University, Shanghai, China; School of Life Sciences, Shanghai University, Shanghai, China; College of Life Sciences, Dezhou University, Dezhou, Shandong, China; College of Agriculture and Bioengineering, Heze University, Heze, Shandong, China; Department of Preventive Medicine, Heze Medical College, Heze, Shandong, China; Shaoxing Institute of Shanghai University, Shaoxing, Zhejiang, China. Electronic address:
Neuronal hyperexcitability in the rostral ventrolateral medulla (RVLM), driven by oxidative stress, plays a crucial role in stress-induced hypertension (SIH). While resveratrol (RSV) is known for its antioxidant properties, its effects on RVLM neurons in SIH remain unclear. We investigated this using an SIH rat model exposed to electric foot shocks and noise stimulation for 15 days.
View Article and Find Full Text PDFThe complex role of oxytocin in fear acquisition and generalization.
Psychoneuroendocrinology
March 2025
Institution for Brain and Psychological Science, Sichuan Normal University, Chengdu 610066, China; Center for Neurogenetics, Shenzhen Institute of Neuroscience, Shenzhen 518057, China. Electronic address:
Fear is an adaptive response that protects individuals from potential threats, but when excessive, it can lead to mental health disorders such as generalized anxiety disorder. Oxytocin is a neuromodulator whose effects on fear processing have been explored, although research results are inconsistent. Previous research indicates that administering oxytocin before fear acquisition can enhance fear learning, while studies have suggested a potential for reducing fear generalization when oxytocin is given after fear acquisition.
View Article and Find Full Text PDFChanges in marital and health status as risk factors for a subsequent negative wealth shock: A population-based longitudinal study in the United States, 1995-2020.
Soc Sci Med
March 2025
Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI, USA; Center for Social Epidemiology and Population Health, University of Michigan School of Public Health, Ann Arbor, MI, USA; Institute for Social Research, University of Michigan, Ann Arbor, MI, USA. Electronic address:
Objectives: A negative wealth shock, defined as a loss of ≥75% in equivalized household total wealth over a short period, may cause adverse health outcomes for older adults. The individual-level risk factors for experiencing a negative wealth shock in later adulthood are unclear.
Methods: Data were from 25,072 adults aged ≥55 in the longitudinal, population-based US Health and Retirement Study from 1995 to 2020 (n = 123,651 observations across all study respondents).
Protocol for cell-type-specific single-cell labeling and manipulation in Drosophila using a sparse driver system.
STAR Protoc
March 2025
Department of Biology and Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA.
Here, we present a protocol for cell-type-specific single-cell labeling and manipulation in Drosophila using a sparse driver system. We describe steps for generating constructs and fly lines, titrating heat-shocked durations for precise temporal control and desired sparsity, and co-expressing multiple transgenes for experiments. We demonstrate that this generalizable toolkit enables tunable sparsity, multi-color staining, single-cell trans-synaptic tracing, single-cell manipulation, and cell-autonomous gene function analysis.
View Article and Find Full Text PDFCardiac herniation identified without any symptoms following extrapleural pneumonectomy: a case report.
Gen Thorac Cardiovasc Surg Cases
March 2025
Division of Thoracic Surgery, Department of Surgery, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-Cho, Kamigyo-Ku, Kyoto, 602-8566, Japan.
Background: Cardiac herniation, especially right-sided herniation, is a fatal complication which causes sudden hypotension due to obstruction of the vena cava. Here, we describe a case of cardiac herniation identified without any symptoms after right extrapleural pneumonectomy performed for diffuse pleural mesothelioma.
Case Presentation: A 72-year-old man with diffuse pleural mesothelioma underwent a right extrapleural pneumonectomy after chemotherapy.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!