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Barriers to early detection: Insurance denials for breast MRI screening in women with germline BRCA1/2 mutations.
Gynecol Oncol
January 2025
New York University Langone Health, Long Island, Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Mineola, NY, United States of America. Electronic address:
Objectives: Women with germline BRCA1/2 pathogenic variants (gBRCA1/2) are recommended to undergo annual breast MRI and mammography. Our objective was to describe the frequency of insurance denials for annual breast MRIs in women with gBRCA1/2 and determine denial trends.
Methods: Women with gBRCA1/2 following in a high-risk breast cancer clinic with breast MRIs ordered from 2020 to 2021 were identified and cross-referenced with a database of insurance denials.
A reduction in effective population size has not relaxed purifying selection in the human population of Eivissa (Balearic Islands).
Sci Rep
January 2025
Departament de Medicina i Ciències de la Vida, Institut de Biologia Evolutiva (CSIC-UPF), Universitat Pompeu Fabra, Dr. Aiguader 88, Barcelona, 08003, Catalonia, Spain.
Ibiza (Eivissa) is one of the main Balearic Islands in the western Mediterranean. Recent studies have highlighted the genetic distinctiveness of present-day Eivissans within the region and suggested it could be attributed to the genetic drift caused by recent demographic events. Whether this distinctiveness emerged from a differential demographic history, or rather from a bias for sampling in a small geographic region such as Eivissa, remains an open question, together with the understanding of the functional consequences of demography in the island.
View Article and Find Full Text PDFExploring data literacy self-perception among Indonesian high school students.
PLoS One
January 2025
Monash University, Melbourne, Australia.
Data is becoming increasingly ubiquitous today, and data literacy has emerged an essential skill in the workplace. Therefore, it is necessary to equip high school students with data literacy skills in order to prepare them for further learning and future employment. In Indonesia, there is a growing shift towards integrating data literacy in the high school curriculum.
View Article and Find Full Text PDFClinical Manifestations.
Alzheimers Dement
December 2024
John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.
Background: The utility of neuropsychological measures commonly used to diagnose individuals with suspected MCI or AD was recently explored in European cohorts, however their utility in Caribbean Hispanic (CH) populations is not well understood.
Method: Our sample consisted of 507 CH individuals from ongoing studies of Puerto Rican and Cuban American older adults (74%% Female, mean age = 74.1, mean education = 12.
The Nordic-walking mechanism and its explanation of deconfined pseudocriticality from Wess-Zumino-Witten theory.
Nat Commun
January 2025
CP3-Origins, University of Southern Denmark, Odense, Denmark.
The understanding of phenomena falling outside the Ginzburg-Landau paradigm of phase transitions represents a key challenge in condensed matter physics. A famous class of examples is constituted by the putative deconfined quantum critical points between two symmetry-broken phases in layered quantum magnets, such as pressurised SrCu(BO). Experiments find a weak first-order transition, which simulations of relevant microscopic models can reproduce.
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