[Socio-demographic characteristics and vitamin D status in women born before 32 weeks'].

Unlabelled: Deficiency of vitamin D (25-OHD) is a health problem among prematurely born women and their newborns independently of the geographical location of the country.

Objectives: To study serum levels of vitamin D in patients born before 32 weeks and their newborns at birth. To analyse the socio-demographic factors, complications of pregnancy and their relationship with vitamin D status of women.

A study on early-onset neonatal group B streptococcal infection, Bulgaria, 2007-2011.

This study examines neonatal group B streptococcal (GBS) colonization and its relation to early-onset GBS disease (EOGBSD), based upon the experience of leading obstetrics and gynecology centers in Bulgaria. The objectives of the study were to update neonatal colonization rates and to assess relationships between clinically differentiated cases (culture-proven GBS newborns) and risk factors inherent to the infant and mother, using a computerized file. The neonatal GBS colonization rate ranged from 5.

[Blood transfusions suppress erythropoiesis in anemia of prematurity].

Unlabelled: AIM AND TASKS: The major gene regulating erythropoietin /EPO/ synthesis is hypoxia induced factor/HIF/. Proceeding from the assumption that the transfusions /HT/ remove hypoxia due to anemia and inactivate HIF, the aim of the study was to show the decreased activity of erythropoiesis after HT MATERIALS AND METHODS:

Patients: 40 premature infants <34 g.a.

[Respirtory distress in newborns of mothers with factor V-Leiden thrombophilia].

Aim: The main aim of the trial is to determine the frequency of respiratory distress syndrome / RDS/ and disorders of coagulation in infants of mothers with thrombophilia.

Materials And Methods: In 51 newborns of mothers with thrombophilia were evaluated the presence of respiratory distress and maternal-fetal infection /MFI/. The children were divided in two groups: Group I--16 newborns of mothers with thrombophilia and Group II--15 healthy children.

[Frequency, severity and risk factors for bronchopulmonary dysplasia among very low birth weight premature infants admitted in the NICU of the University Obstetrics and Gynecology Hospital, Sofia].

Background: The progress in the perinatology improved the survival rate of the infants with extremely low birth weight and gestational age. Among the most immature of them the frequency of bronchopulmonary dysplasia (BPD) remains high..

[Gestational age of delivery in multiple gestation].

Objectives: The aim of this research was to find out the average gestational age of delivery in multiple pregnancy and to compare the results with world trend.

Material And Methods: Retrospective and prospective comparative analysis was used. The study covered 20 years from 1991 to 2011, included 71114 births, 1436 twins, 67 triplets and I quadruplets.

[A study on early-onset group "B" streptococcal neonatal infection].

The results achieved with 80% reduction in the incidence of early-onset neonatal group B streptococcal (GBS) sepsis following the implementation of the preliminary (1996, 2002) and subsequently the revised (2010) guidelines for intrapartum antibiotic prophylaxis imposed the discussion on a large scale of the updated:--algorithms for GBS screening (35-37 weeks of gestation) with the recommended dosage of penicillin-G for intrapartum antibiotic prophylaxis for women having normal labor and delivery;--algorithms for GBS screening and intrapartum antibiotic prophylaxis for women with preterm labor (PPROM) or premature rupture of membranes (PROM);--intrapartum antibiotic prophylaxis regimens for women with penicillin allergy;--algorithm for management of newborns with respect to risk of early-onset GBS disease. The present study is aimed at studying the distribution of the early-onset GBS disease in our country based on the data of leading obstetrics & gynecology clinics and wards. The aim is to diferrentiate clinically the cases and investigate the influence of the known risk factors on the part of the mother.

["In vitro" babies--dreams, that turned real, but a lot of questions and unknown items].

Unlabelled: In vitro babies bring happiness to a lot of families. Their development, health and social problems are being studied in details.

Objectives: To establish the well being of babies, born at the University Maternity Hospital "Maichin dom" following assisted reproduction (AR), probable risk factors immediately after birth and afterwards.

[Vitamin D levels in maternal--VLBW infants pairs].

Unlabelled: Normal foetal growth depends on sufficient mother's vit D intake. Premature birth interrupts vit D and mineral mother-to-foetus transfer and leads to vit D deficiency and disturbs newborn mineral bone metabolism.

Objectives: To determine vit.

[Osteopenia of prematurity--prophylaxis, diagnostics and treatment].

Unlabelled: Osteopenia of prematurity is a metabolic bone disease of premature infants with birth weight < 1500 g and gestational age < 32 weeks. Sub-optimal bone matrix, poor skeletal support and an increased risk of fractures characterized the disease. Its importance is determined by relatively high frequency--between 30-70% of infants at risk, multifactorial etiology and impact on early and late morbidity of the newborns.

[Protocol - indications for transfusion in newborns with low and extremely low birght weight].

Objectives: Hyporegenerative anaemia of prematurity is the cause of frequent transfusions of packed red blood cells. Wellknown is the effect of inhibiting the erythropoiesis after blood transfusions as well as the risk of transmissive infections. Therefore the main purpose of this study was to work out a protocol - indications for blood transfusions in order to achieve maximal reduction in their incidence with premature babies during their stay in ICU.

[Fracture of clavicle in newborns, an attempt to make prognostic factors].

Unlabelled: The most common bone fracture of the newborn is that of the clavicle - frequency 0.2-3.5% of all births, according to various literature sources.