Petrographical and petrophysical rock typing for flow unit identification and permeability prediction in lower cretaceous reservoir AEB_IIIG, Western Desert, Egypt.

The primary objective of this study is to identify and analyze the petrophysical properties of the newly investigated AEB_IIIG member reservoir in Meleiha West Deep (MWD) Field and to classify it into different rock types. Additionally, this research intends to develop mathematical equations that may be utilized to estimate permeability in uncored sections of the same well or in other wells where core samples are unavailable. The analysis focused on the pore hole records of ten wells that were drilled in MWD Field.

Real-World Data on the Prevalence of Anaplastic Lymphoma Kinase-Positive Non-Small-Cell Lung Cancer in the Middle East and North Africa.

Purpose: Anaplastic lymphoma kinase () gene alterations are potent oncogenic drivers in non-small-cell lung cancer (NSCLC). Tyrosine kinase inhibitors targeting the ALK pathway are effective in treating -positive NSCLC. Around 5% of Asian and White patients with NSCLC have -positive tumors, but rearrangement prevalence data in the Middle East and North Africa (MENA) region are limited.

Infliximab efficacy in rheumatoid arthritis after an inadequate response to etanercept or adalimumab: results of a target-driven active switch study.

Objective: Evaluate efficacy of infliximab with response-driven dosing in patients with active RA.

Research Design And Methods: Patients (n = 203) with active RA despite methotrexate + etanercept/adalimumab, participated in this active-infliximab-switch study. Infliximab 3 mg/kg was infused at Weeks 0, 2, 6, 14, and 22 with escalation to 5 or 7 mg/kg depending on EULAR response at Weeks 14 and 22.

Cervical neurapraxia in elite athletes: evaluation and surgical treatment. Report of five cases.

Object: Neurapraxia, transient posttraumatic paralysis of the motor and/or sensory tracts in the spinal cord, may be a career-ending event in an athlete. Management, rehabilitation, and return-to-play decisions remain controversial.

Methods: Five elite football players were evaluated after experiencing episodes of neurapraxia.

[Morbidity/mortality reviews: assessment of their implementation in one hospital].

Objectives: The objective of this study was to describe the steps involved in establishing a morbidity/mortality review committee (MMRC) to analyze the causes of avoidable deaths or life-threatening complications and the development of plans and protocols to avoid their recurrence.

Methods: The MMRC included physicians from each hospital department. Each member was responsible for organizing departmental meetings to analyze its avoidable deaths and life-threatening complications.

Lumbar microdiscectomy: a historical perspective and current technical considerations.

A historical review is presented of the original descriptions of lumbar discectomy, focusing on the evolution toward a less invasive surgical approach following the introduction of the operating microscope. From the initial work in Europe by Yasargil and Caspar to the popularization of microdiscectomy by Williams and Wilson in the United States, this procedure has successfully reduced operative time, surgical morbidity, and incision size while allowing patients to return to work faster. Emphasis is placed on the importance of a careful preoperative clinical and radiographic evaluation by identifying factors that may help in the prediction of a successful surgical outcome.

The effects of anesthesia on cerebral tissue oxygen tension: use of EPR oximetry to make repeated measurements.

While very useful data can be obtained from measurements of pO2 within various compartments of the vascular system, such measurements do not necessarily provide accurate information on the pO2 in the brain. Anesthetics can significantly affect the tissue pO2 in the brain by several mechanisms involving both delivery and utilization. Electron Paramagnetic Resonance (EPR or ESR) oximetry has the potential for non-invasively carrying out repeated direct measurements of pO2 in tissues during the course of anesthesia.

Carotid stenting versus carotid surgery: a prospective cohort study.

Purpose: To compare the results of carotid stenting and carotid surgery in a consecutive group of 455 patients (482 lesions).

Methods: Between January 1995 and July 2002, 107 patients (114 lesions) were treated with carotid stenting and 348 patients (368 lesions) with carotid surgery. A cerebral protection device was routinely used in the last 46 stent cases.

Intradural convexity chondroma: a case report and review of diagnostic features.

Intradural convexity chondromas are slow-growing tumors of young adults and children. Their symptoms are due to their size and degree of mass effect. They are extra-axial, avascular masses without peritumoral edema.

Totally laparoscopic abdominal aortic aneurysm repair.

Abdominal aortic aneurysm (AAA) resection is a major surgical procedure performed frequently. As a minimal access procedure, laparoscopy has been shown in the field of general surgery to improve a patient's postoperative well-being and to shorten hospital stay. The same benefits could be expected from a laparoscopic approach for AAA repair.

Endovascular procedures under near-real-time magnetic resonance imaging guidance: an experimental feasibility study.

Purpose: The purpose of this study was to assess the feasibility of insertion of endovascular stents and the precision of an open-field interventional magnetic resonance imaging (iMRI) system in an in vivo model.

Methods: A feasibility study was undertaken at a university-affiliated hospital. Three male piglets with an average age of 6 months and a weight between 70 and 77 kg and two 3-month-old male piglets that weighed 40 to 44 kg were anesthetized.

In vitro evaluation of the accuracy of open-configuration MRI in endovascular techniques.

The purpose of this study was to determine the accuracy of an interventional magnetic resonance imaging (iMRI) system to position an endovascular catheter in an in vitro model that simulated an infrarenal aortic aneurysm. Adequate visualization of abdominal aortic aneurysms (AAAs) was shown previously in humans. A dedicated near-real-time imaging protocol readily available on a Signa SP 0.

Prognosis of chronic subdural hematomas.

This article considers factors that may be of prognostic value in evaluating the chronic subdural hematoma (CSH) patient. It also examines conditions that predispose the development of a CSH. Variables such as admission neurologic status and presenting symptomatology are reviewed.

Postoperative complications of chronic subdural hematomas: prevention and treatment.

The treatment of chronic subdural hematoma seems simple and effective; however, postoperative complications like recurrence of hematoma, pneumocephalus brain collapse, and intracervical hemorrhage still occur in some patients, and these complications are dependent on surgical technique, patient's age, and preexisting morbidity.

Laparoscopic-assisted distal ventriculoperitoneal shunt placement.

Background: Intraperitoneal adhesions, obesity, and distorted abdominal anatomy in shunt-dependent hydrocephalic patients are patient characteristics that increase distal ventriculoperitoneal (VP) shunt failure rates. The use of laparoscopic-aided placement of the distal VP catheter as a technique to decrease the failure rate is evaluated in these patients.

Method: Thirteen hydrocephalus patients considered to either have intra-abdominal adhesions, be obese, or have distorted abdominal anatomy underwent laparoscopic-aided distal VP catheter placement or revision.

Analytical and clinical relationships between human IgG autoantibodies to beta 2 glycoprotein I and anticardiolipin antibodies.

Objective: To examine IgG anti-beta 2 glycoprotein I (anti-beta 2 GPI) binding in 82 sera referred for anticardiolipin antibody (aCL) testing and to develop preliminary clinical correlations with antiphospholipid syndrome (APS).

Methods: Immunoassay of IgG cofactor dependent aCL and IgG anti-beta 2 GPI antibodies and retrospective chart review.

Results: Forty-four sera exhibited normal (< or = 22 GPL units) aCL activity, 18 had moderate binding activity (23-45 GPL units), and 20 had high (> or = 46 GPL units) binding activity to cardiolipin.

Binding of beta 2 glycoprotein I to activated polystyrene and its recognition by human IgG autoantibodies.

Beta 2 glycoprotein I (apolipoprotein H, beta 2GPI) is involved in the formation of epitope(s) recognized by clinically relevant autoantibodies from patients with antiphospholipid syndrome. We studied the binding of beta 2GPI to chemically activated polystyrene in a microtitre plate format. Adsorption isotherms (at 37 degrees C) were generated for beta 2GPI on activated polystyrene and on unactivated polystyrene, with both human serum antibodies and rabbit polyclonal IgG antibodies as probes, and horseradish peroxidase (HRP)-tagged anti-IgG to detect binding.

Transport, uptake, and metabolism of blood-borne vasopressin by the blood-brain barrier.

Transport, binding, and metabolism of [phenylalanyl-3,4,5,-3H(N)]arginine vasopressin (AVP) by the blood-brain barrier (BBB) was studied in adult guinea-pigs by means of a novel vascular brain perfusion (VBP)/capillary depletion technique and HPLC. A time-dependent, progressive brain uptake of 3H-radioactivity was measured over the 10 min period of VBP both in brain homogenates and in brain tissue depleted of cerebral microvessels. The unidirectional blood-to-brain transport constant, K(IN), estimated by multiple-time tissue uptake analysis of the homogenate and postcapillary supernatant, indicated that the BBB transfer rate for [3H]AVP (K(IN) = 2.

Radionecrosis secondary to interstitial brachytherapy: correlation of magnetic resonance imaging and histopathology.

Radiation-induced tissue damage in the central nervous system is a well-known complication of interstitial brachytherapy for brain tumors, yet imaging correlates have historically been based upon computed tomographic scans. We now present magnetic resonance imaging (MRI) to correlate radiation changes after interstitial brachytherapy with the histopathology. The central nervous system of a 38-year-old man with a left frontal cerebral glioma diagnosed by stereotactic biopsy was treated with interstitial brachytherapy (iridium-192, 47 Gy), followed by limited-field irradiation (45 Gy).