Effects of individualized resistance training prescription with heart rate variability on muscle strength, muscle size and functional performance in older women.

Introduction: This study aimed to investigate whether individualizing autonomic recovery periods between resistance training (RT) sessions (IND) using heart rate variability (HRV), measured by the root mean square of successive R-R interval differences (RMSSD), would lead to greater and more consistent improvements in muscle strength, muscle mass, and functional performance in older women compared to a fixed recovery protocol (FIX).

Methods: Twenty-one older women (age 66.0 ± 5.

Beta-Alanine for Improving Exercise Capacity, Muscle Strength, and Functional Performance of Older Adults: A Systematic Review.

Background/objective:  Beta-alanine supplementation increases muscle carnosine content and also improves exercise capacity and performance in young adults, with mixed findings emerging from the few studies investigating its effects on older participants. Therefore, this study aimed to systematically review the evidence regarding the effects of beta-alanine on exercise capacity, muscle strength, and functional performance of older adults.

Methods:  This systematic review was conducted following the specific methodological guidelines of the Preferred Report Items for Systematic Reviews and Meta-Analyses and the Physiotherapy Evidence Database scale.

The Sire Effect on Gestational Length in Wagyu Cattle.

This study investigated the factors influencing gestation length in a herd of Wagyu cattle in Rio Grande do Sul, Brazil. Fifty-five multiparous purebred Wagyu cows underwent a Fixed-Time Artificial Insemination (FTAI) protocol using semen from a bull randomly selected from five bulls representing three distinct genetic lines. Following birth, we recorded the calves' gender, weight, and gestation length.

Relationship between characteristics of health professionals and the respect for the autonomy of cancer patients at the end of life.

Background And Aim: This study investigated whether providers respected patient's autonomy, investigating providers' pattern of decisions and their associated characteristics.

Methods: Cross-sectional study, conducted through anonymous questionnaire with hypothetical clinical cases, presented to providers at one oncology center. Decision-making patterns were pre-stablished accordingly to the response´s pattern.

Uncoupling as initiating event in mitochondrial dysfunction after diuron exposure.

Diuron, a herbicide derived from urea, has been shown to induce urinary bladder urothelial tumors in rodents, leading the U.S. Environmental Protection Agency (USEPA) to designate it as a 'known/likely' human carcinogen.

Interprofessional education in traditional and complementary medicine: a scoping review.

Interprofessional education (IPE) is a teaching method that improves collaboration and communication across health professions. There are consistent reports of poor interprofessional collaboration and communication between conventional health professionals and traditional and complementary medicine (TCM) professions. The application of IPE within courses that provide training in TCM requires close examination.

The microbiome effect on the female reproductive performance.

The female reproductive function is coordinated by the endocrine system driven by the hypothalamic-pituitary-gonadal (HPG) axis. While not directly part of the female reproductive system, the gut microbiome plays a crucial role in overall health, including reproductive health. The gut microbiome communicates bidirectionally with the brain via the gut-brain axis, influencing stress levels, mood, and hormonal balance, which can impact reproductive health and fertility.

A retrospective chart review to identify the involvement of palliative care with glioblastoma multiforme patients.

Background: Glioblastoma Multiforme is a deadly brain cancer that is very challenging for patients and their families. It is associated with rapid progression, cognitive decline, and a low survival rate.

Objective: To determine whether deceased Glioblastoma Multiforme patients had received follow-up service from the palliative care team before their death, whether invasive measures had been reduced, and whether the last antineoplastic treatment was given within 14-30 days before death.

Association of hypermagnesemia at birth and admission hypothermia in pre-term infants: A secondary analysis of a prospective cohort study.

Background: Hypothermia on admission is associated with increased mortality in preterm infants. Drugs administered to pregnant women is implicated in its occurrence. Since magnesium sulfate has a myorelaxant effect, we aimed evaluating the association of hypermagnesemia at birth and admission hypothermia (axillary temperature <36.

Enhancing RECK Expression Through miR-21 Inhibition: A Promising Strategy for Bladder Carcinoma Control.

Bladder carcinoma (BC) is the tenth most frequent malignancy worldwide, with high morbidity and mortality rates. Despite recent treatment advances, high-grade BC and muscle-invasive BC present with significant progression and recurrence rates, urging the need for alternative treatments. The microRNA-21 (miR-21) has superexpression in many malignancies and is associated with cellular invasion and progression.

Upregulation of shelterin and CST genes and longer telomeres are associated with unfavorable prognostic characteristics in prostate cancer.

Introduction: Search for new clinical biomarkers targets in prostate cancer (PC) is urgent. Telomeres might be one of these targets. Telomeres are the extremities of linear chromosomes, essential for genome stability and control of cell divisions.

Evaluation of AR, AR-V7, and p160 family as biomarkers for prostate cancer: insights into the clinical significance and disease progression.

Purpose: To assess the role of the p160 family, AR, and AR-V7 in different initial presentations of prostate cancer and their association with clinical endpoints related to tumor progression.

Methods: The study sample comprises 155 patients who underwent radical prostatectomy and 11 healthy peripheral zone biopsies as the control group. Gene expression was quantified by qPCR from the tissue specimens.

Diuron and its metabolites induce mitochondrial dysfunction-mediated cytotoxicity in urothelial cells.

In the environment, or during mammalian metabolism, the diuron herbicide (3-(3,4-dichlorophenyl)-1,1-dimethylurea) is transformed mainly into 3-(3,4-dichlorophenyl)-1-methylurea (DCPMU) and 3,4-dichloroaniline (DCA). Previous research suggests that such substances are toxic to the urothelium of Wistar rats where, under specific exposure conditions, they may induce urothelial cell degeneration, necrosis, hyperplasia, and eventually tumors. However, the intimate mechanisms of action associated with such chemical toxicity are not fully understood.

Association between anti-Müllerian hormone levels and reproductive parameters in Wagyu cattle raised in Brazil.

The production of embryos has sped up the dissemination of superior genetic material. However, the variation among the cattle response to oocyte and embryo production is a challenging factor. This variation is even higher in the Wagyu cattle as the breed has a small effective population size.

Muscle Hypertrophy Responses to Changes in Training Volume: A Retrospective Analysis.

This study assessed associations between changes in the weekly number of sets performed and the percentage change in muscle thickness of the biceps (MT) and triceps (MT) brachii muscles. Through a retrospective analysis, sixty-eight resistance-trained subjects that participated in previous studies had their previous training volumes analyzed and compared to the volume imposed during each individual study. The relationship between variables was determined through correlation and a k-cluster analysis was performed to subdivide the participants into three groups and classified as:<0%; 0-50%, and >50% increase in the number of sets for both muscle groups.

Protein Supplementation in Addition to Strength Training Programs for Improving Body Composition in Older Adults: What Else Is Left to Know? A Brief Update Review of the Current Evidence.

Resistance training alongside proper protein intake is an important tool to mitigate the deleterious effects of the aging process on skeletal muscle tissue. However, it is not completely elucidated whether adding protein supplementation provides further improvements on body composition outcomes of older adults during resistance training programs. The present narrative review aimed to describe the most recent evidence regarding the effects of protein supplementation on both lean body mass and fat mass of older adults and to provide insight into how health professionals may use this information to properly design nutritional programs for this population.

Chronic Effects of Inter-Set Static Stretching on Morphofunctional Outcomes in Recreationally Resistance-Trained Male and Female.

: The purpose of this study was to compare the effects of resistance training (RT) with inter-set static stretching (IS) versus traditional RT (TRT) on morphofunctional outcomes in recreationally resistance-trained male and female. : Twenty-two recreationally-trained subjects were allocated to IS group (n = 12) or TRT (n = 10) and completed eight weeks of RT. The only difference between the groups was that IS group included static stretching between sets, while the TRT rested between the sets.

Does beta-alanine supplementation enhance adaptations to resistance training? A randomized, placebo-controlled, double-blind study.

The aim of the present study was to assess the effects of beta-alanine supplementation on muscle strength and thickness. Nineteen resistance-trained men (age: 27.3 ± 5.

A novel stress-based intervention reduces cigarette use in non-treatment seeking smokers.

Tobacco use is the leading cause of preventable mortality worldwide. Since current smoking cessation aids show only modest efficacy, new interventions are needed. Given the evidence that stress is a potent trigger for smoking, the present randomized clinical trial tested whether stress could augment the effects of a memory updating (retrieval-extinction) intervention.

Manipulating Resistance Training Variables to Induce Muscle Strength and Hypertrophy: A Brief Narrative Review.

The regular practice of resistance training (RT) has been shown to induce relevant increases in both muscle strength and size. In order to maximize these adaptations, the proper manipulation of RT variables is warranted. In this sense, the aim of the present study was to review the available literature that has examined the application of the acute training variables and their influence on strength and morphological adaptations of healthy young adults.

An Examination of Two Resistance Training Frequency Techniques in Morphological and Functional Adaptations of the Patellar Tendon.

The aim of the present study was to investigate the effects of distinct resistance training frequencies with equated-volume conditions in morphological and functional adaptations of the patellar tendon. Twenty-seven recreationally resistance-trained subjects (men [n=17] and women [n=10]) (age: 20.8 ± 1.

Protein Supplementation for Strength and Functionality in Older Adults: Is There Still Any Doubt? A Brief Update Review.

It is widely known that the aging process induces relevant impairments on both muscle morphology and function. In this sense, resistance training alongside proper protein intake are important strategies to mitigate the sarcopenia process in older individuals. However, adding protein supplementation (PS) to resistance training interventions for enhancing muscle strength and functional performance has shown mixed results in this population.

Survie des patients en oncologie traités par l'équipe de soins palliatifs d'un hôpital de São Paulo, au Brésil.

Introduction: L'échelle de l'indice fonctionnel de Karnofsky (Karnofsky Performance Status Scale) est un instrument d'évaluation pertinent et fonctionnel qui sert à déterminer quelles personnes devraient être suivies par des équipes multidisciplinaires de soins palliatifs.

Objectif: Analyser les résultats cliniques de patients, suivis par une équipe de soins palliatifs, dont l'indice fonctionnel de Karnofsky est inférieur à 70 %, et les comparer aux résultats de personnes n'ayant pas bénéficié de ce type de soins.

MÉthodologie: Dans la présente étude de cohorte rétrospective, le suivi pendant 10 jours des patients par l'équipe de soins palliatifs constituait le facteur d'exposition et la survie, la variable dépendante.