Dietary pattern, physical activity and body composition of Children with and without Down Syndrome - A case control study.

Down syndrome (DS) is a known chromosomal disorder that results in changes in physical and clinical characteristics. Subjects with DS are more likely to be obese or overweight and have some recognized nutrition related problems. The objectives of this study are to compare body composition, food consumption pattern and physical activity level of children with and without DS.

The Effect of Breastfeeding on Intelligence Quotient and Social Intelligence Among Seven- to Nine-Year-Old Girls: A Pilot Study.

Background: Breastfeeding is an optimal infant feeding method that provides adequate nutrients, achieves healthy growth and development, and enhances the health status of both infants and mothers. Breast milk contains a variety of substances that might positively affect cognition and the development of children's psychomotor abilities.

Objective: This study aimed to examine the variations in intelligence quotient (IQ), social intelligence (SI), and body mass index (BMI) among 7- to 9-year-old girls who were exclusively breastfed, exclusively bottle-fed, or mixed-fed during their first 6 months of life.

Associations of BMI, waist circumference, body fat, and skeletal muscle with type 2 diabetes in adults.

Aims: Type 2 diabetes (T2D) is known to be associated with high BMI and waist circumference (WC). These measures do not discriminate well between skeletal muscle (SM) and body fat (BF), which may have opposite influences.

Methods: We conducted a secondary analysis of population-based data from 58,128 aged 18-85 yrs from Scottish Health Surveys (2003, 2008-2011) and Health Surveys for England (2003-2006, 2008-2013), excluding pregnant women and insulin-treated diabetes.

Associations of body fat and skeletal muscle with hypertension.

Hypertension is known to be associated with obesity, while its relationship to skeletal muscle, SM (SM; a marker of general health and body function), remains uncertain. We analyzed population-based data of 22 591 men (mean age: 51.6 ± 16.

Derivation and validation of simple anthropometric equations to predict adipose tissue mass and total fat mass with MRI as the reference method.

The reference organ-level body composition measurement method is MRI. Practical estimations of total adipose tissue mass (TATM), total adipose tissue fat mass (TATFM) and total body fat are valuable for epidemiology, but validated prediction equations based on MRI are not currently available. We aimed to derive and validate new anthropometric equations to estimate MRI-measured TATM/TATFM/total body fat and compare them with existing prediction equations using older methods.

Derivation and validation of simple equations to predict total muscle mass from simple anthropometric and demographic data.

Background: Muscle mass reflects and influences health status. Its reliable estimation would be of value for epidemiology.

Objective: The aim of the study was to derive and validate anthropometric prediction equations to quantify whole-body skeletal muscle mass (SM) in adults.

Predicting muscle mass from anthropometry using magnetic resonance imaging as reference: a systematic review.

Identification and management of sarcopenia are limited by lack of reliable simple approaches to assess muscle mass. The aim of this review is to identify and evaluate simple methods to quantify muscle mass/volume of adults. Using Cochrane Review methodology, Medline (1946-2012), Embase (1974-2012), Web of Science (1898-2012), PubMed, and the Cochrane Library (to 08/2012) were searched for publications that included prediction equations (from anthropometric measurements) to estimate muscle mass by magnetic resonance imaging (MRI) in adults.

Intestinal inflammation in rats induces metallothionein in colonic submucosa.

The aim of the current study was to determine if induction of metallothionein (MT) via acute or chronic dietary zinc supplementation attenuates intestinal inflammation, and to investigate the relationship with site-specific intestinal MT determined by immunolocalization. Growing rats were assigned to zinc-deficient (ZD), acute zinc-treated (ZT), pair-fed, control or chronic Zn-supplemented (ZS) groups. Half the rats in each dietary group received 5% dextran sulphate sodium (DSS) in their drinking water for 4 days.

Gastric malignancy: clinicopathologic spectrum and relationship to Helicobacter pylori infection.

Background: Upper gastrointestinal cancer particularly of stomach is a relatively frequent form of cancer. Gastric H pylori infection has been implicated in the pathogenesis of both gastric carcinoma and gastric lymphoma. Gastric carcinoma has been addressed by many articles in the Kingdom of Saudi Arabia (KSA) and the Middle East, while only a few addressed gastric lymphoma.

Research and research activities in a university in Eastern Saudi Arabia.

Objectives: The purpose of the present study was to obtain the views of faculty members regarding various aspects of scientific research, which is one of the essential functions of a University.

Methods: A cross-sectional study was conducted in the College of Medicine, King Faisal University, Dammam, Kingdom of Saudi Arabia, between January and June 2001, using a standardized questionnaire to obtain the views of faculty members in both basic and clinical departments on issues related to scientific research. The questionnaire consisted of 41 items and the responses were assessed on a 5 point scale.

Undergraduate curriculum reform in Saudi medical schools. Which direction to go?

Curriculum reform in undergraduate medical education is quite essential for the success of the educational process. Saudi medical schools have been involved in curriculum reform over the past 2 decades. Review of the existing literature identifies the following as problems with today's curriculum including: Overcrowding of the curriculum, over presentation of some subjects, presence of relatively non-relevant subjects, dissociation between basic and clinical sciences, repetition of lectures and exams, need for new subjects of clinical relevance, predominantly hospital based medical education with minimal community-based practice, as well as non-optimal use of resources.

The pattern of lower gastrointestinal disease in the eastern region of Saudi Arabia: a retrospective analysis of 1590 consecutive patients.

To determine the pattern of lower gastrointestinal disease in the Eastern region of Saudi Arabia we analysed 1907 colorectal biopsies obtained from 1590 consecutive patients (1256 males & 334 females), evaluated during a 13 year period (1983-1996) in a tertiary care teaching hospital. The age range was 6-81 years with a mean of 37 + 15. During the same period 6874 new patients were seen in the Gastroenterology Clinics.

Treatment of cutaneous leishmaniasis with antimony: intramuscular versus intralesional administration.

The various methods used to treat cutaneous leishmaniasis (CL) have not given consistent results. The aim of the present study was to compare the efficacy of a solution of meglumine antimoniate (MA; 85 mg Sb/ml) given intralesionally (i.l.

Undergraduate Curriculum Reform in Saudi Medical Schools, needed or not?

Full text is available as a scanned copy of the original print version.

Chronic idiopathic ulcerative colitis in Saudi Arabia: A clinicopathological study of 76 cases.

In this report we present our experience with 76 cases of chronic idiopathic ulcerative colitis (IUC) out of 1279 consecutive colorectal biopsies (6.0%), seen during an 11-year period (1983-1994), in a tertiary care teaching hospital. During the same period, 12 (0.

Crohn's disease in Saudi Arabia: a clinicopathological study of 12 cases.

In this report we present our experience with 12 cases of Crohn's disease out of 1279 consecutive colorectal biopsies (0.9%), seen during an l 1 years period (1983-1994) in a tertiary care teaching hospital. During the period 76 cases (6%) of Ulcerative Colitis (UC) were seen.

Osteoarthritis of the knee among Saudi Arabian security forces personnel.

The prevalence and pattern of osteoarthritis of the knee and its association with obesity among security forces personnel was investigated. A single survey with a control group was done at the Mobile Hospital, Ministry of Interior, Makkah Al Mukarramah. One hundred twenty-five patients presenting to the orthopedic clinic with painful knees of at least 12 months duration gave detailed histories and were treated with bi-planar conventional radiography; they were matched with a similar number from the clinics of internal medicine without painful knees.

A randomized, double-blind, clinical trial of topical clotrimazole versus miconazole for treatment of cutaneous leishmaniasis in the eastern province of Saudi Arabia.

The parenteral treatment currently available for cutaneous leishmaniasis (CL) is painful and potentially exposes patients to serious side effects. Thus, effective, topical therapy would be valuable. We assessed the efficacy of topical 1% clotrimazole and 2% miconazole creams in relation to early healing of lesions in CL in a randomized, double-blind clinical trial in 54 patients with 151 lesions treated for 30 consecutive days.

Inflammatory bowel disease: medical management.

Various papers have been published on inflammatory bowel disease in the Kingdom of Saudi Arabia and other Gulf States during last decade. Apparently, the published data contradict previous belief and indicate that, we might deal here with a medical problem. However, data on the magnitude of this disease in our community remains uncertain.

Pattern of chronic liver disease in the eastern province of Saudi Arabia. A hospital-based clinicopathological study.

During the period 1982-1990, 544 patients with clinical evidence of liver disease were admitted to King Fahd University Hospital, Al-Khobar, Saudi Arabia. Besides routine laboratory and sonographic investigations, all were subjected to either a needle liver biopsy, laparoscopy or a laparotomy. The tissue diagnoses were as follows: liver cirrhosis 17.

Abdominal tuberculosis in Saudi Arabia: a clinicopathological study of 65 cases.

The clinical and pathological features of 65 patients with abdominal tuberculosis obtained during a 7-yr period were analyzed and the diagnostic procedures critically evaluated. The diagnosis was histologically confirmed in 59 patients. In two more patients, the diagnosis was based solely on a positive ascitic fluid culture for tubercle bacilli.

Subacute toxicity of pentavalent antimony compounds in rats.

A subacute toxicity study of pentavalent antimony (Sb) compounds, sodium stibogluconate (SSG) and meglumine antimoniate (MA) was carried out in rats. Three groups of 10 rats each were treated with saline (control group), 300 mg Sb kg-1 d-1 or 900 mg Sb kg-1 d-1 of SSG for 30 d. A parallel study of similar type was conducted for MA.

Hepatic encephalopathy in Saudi Arabia: retrospective analysis of 51 patients.

The clinical features, prognostic factors, and outcome of 51 patients with hepatic encephalopathy (HE), were retrospectively reviewed. The mean (+/- SD) age of patients was 47.2 (+/- 14.

Evaluation of topical ketoconazole in cutaneous leishmaniasis.

The efficacy of topical ketoconazole in cutaneous leishmaniasis (CL) caused by L. major was assessed in an open trial. Ten patients with twenty two lesions of CL, confirmed by smear/or biopsy, were recruited into the study.