Publications by authors named "Zuzana Ozanova"
An inability of the human body to heal acute wounds under certain conditions results in the formation of chronic ulcers. Chronic wounds not only cause significant pain and discomfort for patients but also serve as an entry for microorganisms into the human body, which can result in serious life-threatening problems and become a significant burden for the patients and society. The current work present results of a multicentre prospective observational study demonstrating the use of a lyophilized amniotic membrane (AM) in the treatment of chronic wounds (various etiologies).
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- The long non-coding RNA TUG1 is found to be overexpressed in high-grade muscle-invasive bladder cancer (MIBC) tumor tissues compared to adjacent non-tumor tissues.
- Increased levels of TUG1 are linked to metastatic tumors and are associated with shorter overall survival rates for MIBC patients.
- In vitro experiments show that silencing TUG1 reduces cancer cell proliferation and migration, suggesting its potential as a biomarker or therapeutic target in MIBC.