Atypical meningioma with destruction of cervical vertebrae inside the spinal canal: A case report and literature review.

Atypical meningioma is a specific type of meningioma that is relatively rare in clinical practice. The clinical manifestations of atypical meningioma are non-specific and the imaging findings are similar to those for other intraspinal space-occupying lesions. It is usually misdiagnosed as schwannoma or metastases, and it is necessary to rely on intraoperative findings and pathological examination to confirm the diagnosis.

[Protective effects of Purα on rat hippocampus DNA damage induced by epilepsy].

Objective: To investigate the protective effects of Purα protein on rat hippocampus DNA damage induced by epilepsy and the effects of Purα protein on the repair of DNA damage.

Methods: The Purα overexpressing and siRNA lentiviruses were packaged in vitro and the high tittered virion was injected into rat hippocampus guided by stereotaxic apparatus. 14 days later after the lentivirus injection, epileptic onset is induced by intraperitoneal injection of pilocarpine.