Publications by authors named "Zuoyao Wu"
Deoxynivalenol (DON), a Fusarium mycotoxin, causes spleen apoptosis and inflammation, which damage the organ. Curcumin (Cur) is a member of the ginger family. It has anti-apoptotic and anti-inflammatory effects that maintain the health of the organism's immune system.
View Article and Find Full Text PDFThermosensitive Injectable Dual Drug-Loaded Chitosan-Based Hydrogels for Treating Bacterial Endometritis.
ACS Biomater Sci Eng
December 2024
Article Synopsis
- Endometritis is a common condition in female animals that impacts their reproductive health, often caused by certain bacteria.
- Researchers developed a thermosensitive hydrogel made of chitosan and β-glycerophosphate infused with two drugs, berberine and carvacrol, to treat this condition.
- The hydrogel quickly forms at body temperature, is easy to inject, and releases the drugs over time while showing effectiveness against bacteria and reducing infection-related damage in the uterus.
Deoxynivalenol (DON) poses a serious global food safety risk due to its high toxicity and contamination rate. It disrupts the intestinal epithelial barrier, allowing exogenous toxins to enter the circulation and resulting in sepsis and systemic toxicity. In this research, 32 male Kunming mice and Porcine Small Intestinal Epithelial (IPEC-J2) cells were treated with DON at 0-4.
View Article and Find Full Text PDF