Bioactive NbC MXene-Functionalized Hydrogel with Microenvironment Remodeling and Enhanced Neurogenesis to Promote Skeletal Muscle Regeneration and Functional Restoration.

The complete structure-functional repair of volumetric muscle loss (VML) remains a giant challenge and biomedical hydrogels to remodel microenvironment and enhance neurogenesis have appeared to be a promising direction. However, the current hydrogels for VML repair hardly achieve these two goals simultaneously due to their insufficient functionality and the challenge in high-cost of bioactive factors. In this study, a facile strategy using NbC MXene-functionalized hydrogel (OPTN) as a bioactive scaffold is proposed to promote VML repair with skeletal muscle regeneration and functional restoration.

Ceria Nanoenzyme-Based Hydrogel with Antiglycative and Antioxidative Performance for Infected Diabetic Wound Healing.

Diabetic wound healing still faces a dilemma because of the hostile hyperglycemic, oxidative, and easily-infected wound microenvironment. In addition, advanced glycation end products (AGEs) further impede wound repair by altering the immunological balance. Herein, ceria nanorods with distinctive antiglycative and excellent antioxidative capacities are innovatively introduced into a self-healing and erasable hydrogel, which could reshape the wound microenvironment by expediting hemostasis, inhibiting infection, reducing AGEs, and continuously depleting reactive oxygen species.

Cobalt-Iron Double Ion-Bovine Serum Albumin Chelation-Assisted Thermo-Sensitive Surface-Imprinted Nanocage with High Specificity.

To develop multifunctional protein imprinted materials, a cobalt-iron double ion-BSA directional chelation-assisted thermo-sensitive surface-imprinted hollow nanocage (Co-Fe@CBMA-MIPs) with excellent specificity is developed on the surface of ZIF-67@Co-Fe in this study by synergizing the advantages of surface imprinting, metal ion chelation, anti-protein adsorption segments, and thermo-sensitive components. Beyond previous research, well-designed multifunctional protein-imprinted materials possess high binding capacity, fast adsorption kinetics, and outstanding selectivity. When the adsorption is carried out at 32 °C, the adsorption capacity of Co-Fe@CBMA-MIPs for BSA reaches 520.

Development of surface imprinted heterogeneous nitrogen-doped magnetic carbon nanotubes as promising materials for protein separation and purification.

To promote the development of molecular imprinting technique in the separation and analysis of protein, novel bovine serum albumin (BSA) surface imprinted nitrogen-doped magnetic carbon nanotubes (N-MCNTs@MIPs) are developed by this paper. The imprinted materials are prepared by depositing polydopamine (PDA) on the surface of nitrogen-doped magnetic carbon nanotubes (N-MCNTs). N-MCNTs prepared by high temperature pyrolysis and chemical vapor deposition exhibit high specific surface area, positive hydrophilicity, abundant nitrogen functional groups and excellent magnetic properties.

Preparation of BSA surface imprinted manganese dioxide-loaded tubular carbon fibers with excellent specific rebinding to target protein.

Along with the wide development of protein imprinted polymers, the researchers still face many challenges, such as difficult template elution, slow adsorption rate and low adsorption capacity. In order to promote the progress of protein separation and purification, the surface imprinted manganese dioxide-loaded tubular carbon fibers (FTCFs@MnO@MIPs) are prepared in this work. FTCFs@MnO@MIPs are based on tubular carbon fibers (TCFs) coated with flaky MnO.

Preparation of CTCNFs/CoS hybrid nanofibers with enhanced microwave absorption performance.

A three-step synthesis strategy has been applied to the preparation of CoS-loaded tubular carbon nanofibers (CTCNFs/CoS hybrid nanofibers) with excellent microwave absorbing ability. Firstly, tubular polymer nanofibers (TPNFs) are synthesized using the confined self-condensation method that we developed. Afterwards, TPNFs are converted into surface carboxylated tubular carbon nanofibers (CTCNFs) by carbonization and subsequent acidification processes.

Surface Microstructure Regulation of Porous Polymer Microspheres by Volume Contraction of Phase Separation Process in Traditional Suspension Polymerization System.

In the present work, the suspension polymerization method is used for the preparation of porous polymer microspheres with different surface morphology, and the preparation mechanism is systematically expounded. The morphology results show that the smooth, convex, and wrinkled microspheres could be controlled by adjusting the ratio of monomer to porogens. The micelles forming the framework support the "Eggshell," and its size and shape directly affect the morphology of "Eggshell.