Identification of NAD Metabolism-Derived Gene Signatures in Ovarian Cancer Prognosis and Immunotherapy.

Nicotinamide adenine dinucleotide (NAD) has emerged as a critical regulator of cell signaling and survival pathways, affecting tumor initiation and progression. In this study it was investigated whether circulating NAD metabolism-related genes (NMRGs) could be used to predict immunotherapy response in ovarian cancer (OC) patients. In this study, NMRGs were comprehensively examined in OC patients, three distinct NMRGs subtypes were identified through unsupervised clustering, and an NAD-related prognostic model was generated based on LASSO Cox regression analysis and generated a risk score (RS).

Lymphatic leakage after pelvic lymphadenectomy for cervical cancer: a retrospective case-control study.

Background: The study aims to evaluate the clinical features and management of postoperative lymphatic leakage (PLL) in patients with cervical cancer who received pelvic lymphadenectomy.

Methods: This retrospective study screened consecutive patients with cervical cancer (stage Ia2-IIb).

Results: Among 3427 cases screened, 63 patients (1.