Oxidative stress impairs the meat quality of broiler by damaging mitochondrial function, affecting calcium metabolism and leading to ferroptosis.

Objective: This work was conducted to investigate the effects of oxidative stress on meat quality, mitochondrial function, calcium metabolism and ferroptosis of broilers.

Methods: In this study, a total of 144 one-day-old male Ross 308 chicks were divided into 3 groups (control group, saline group, and hydrogen peroxide [H2O2] group) with 6 replicates of 8 broilers each. The study lasted for 42 d.

Oxidative stress induced by hydrogen peroxide promotes glycolysis by activating CaMKK/LKB1/AMPK pathway in broiler breast muscle.

Oxidative stress is common in the whole process of broiler production, and breast muscle is one of the target organs most vulnerable to oxidative attack. When broilers are subjected to oxidative stress, the regulation of adenosine 5-monophosphate activated protein kinase (AMPK) is a critical path to maintain the dynamic balance of intracellular energy. However, whether calcium/calmodulin-dependent protein kinase (CaMKK) and liver kinase B1 (LKB1) are involved in the regulation of AMPK activation in broiler breast muscle under oxidative stress has not been elucidated.

Hydrogen peroxide-induced oxidative stress impairs redox status and damages aerobic metabolism of breast muscle in broilers.

Oxidative stress has always been a hot topic in poultry science. However, studies concerning the effects of redox status and glucose metabolism induced by hydrogen peroxide (HO) in the breast muscle of broilers have been rarely reported. This study was aimed to evaluate the impact of intraperitoneal injection of HO on oxidative damage and glycolysis metabolism of breast muscle in broilers.

Effects of recombinant swollenin on the enzymatic hydrolysis, rumen fermentation, and rumen microbiota during in vitro incubation of agricultural straws.

An experiment was conducted to determine the effects of swollenin on the enzymatic hydrolysis and in vitro rumen microbial fermentation of agricultural straws. The swollenin from Trichoderma reesei was produced in Pichia pastoris in current study. The recombinant protein caused an obvious disruption on filter paper and slight increase in reducing sugars release when treating xylan, Avicel, rice straw, wheat straw, and corn straw.

Downregulation of microRNA 99a in oral squamous cell carcinomas contributes to the growth and survival of oral cancer cells.

MicroRNAs (miRNAs) are small non-coding RNA molecules that regulate gene expression by either translational inhibition or mRNA degradation. miRNAs play pivotal roles in physiological functioning and pathological progression. The function of microRNA-99a (miR-99a) in oral squamous cell carcinoma (OSCC) remains unclear.