Publications by authors named "Zuo-wei Yuan"
Article Synopsis
- Phenotypic assays of hepatitis B virus (HBV) are crucial for studying drug resistance during long-term treatment of chronic hepatitis B.
- A new cloning strategy using a "fragment substitution reaction" (FSR) simplifies the process of creating replication-competent HBV recombinants from clinical isolates.
- Using this new method, researchers conducted a phenotypic assay on an HBV strain with a specific mutation, finding that it shows in vitro sensitivity to entecavir despite previously being only partially responsive.
