Publications by authors named "Zuo-Qing Song"
To explore the mechanisms for steep pulse irreversible electroporation technology to kill the lung cancer cell L9981. The apoptosis, cells mitochondrial membrane potential, internal PH changes and the intra-cellular calcium ions concentration were detected after steep pulses acted on the human large cell lung cancer cell L9981. Apoptosis test results indicated that cancer cells mainly experienced necrosis and apoptosis.
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- The study focused on the insulin-like growth factor 2 (IGF2) gene and its loss of imprinting (LOI) in 90 gastric cancer patients compared to 90 non-cancer controls.
- IGF2 LOI was found in 48.5% of primary tumor tissues and was associated with advanced stage gastric tumors but did not significantly impact survival rates.
- The research suggests that LOI of IGF2 may contribute to gastric cancer development by increasing IGF2 expression, indicating its potential as a clinical marker for identifying individuals at higher risk for the disease.