Publications by authors named "Zuo Ding"

Article Synopsis
  • - This study created a quick and cost-effective method using melamine functionalized gold nanoparticles (MA-Au NPs) to detect amikacin in milk, showcasing their ability to change color in response to the antibiotic.
  • - The MA-Au NPs were analyzed through various techniques, revealing a specific absorption peak and optimal reaction conditions, ensuring accurate detection with minimal limits of detection.
  • - The developed method demonstrated high accuracy and reliability, with successful application in real milk samples, making it an easy and practical solution for monitoring amikacin levels.
View Article and Find Full Text PDF

A colorimetric sensor for the rapid and sensitive detection of GSH was developed. The hydrothermal method was utilized to synthesize chitosan-stabilized gold nanoparticles (CS-AuNPs). The synthesized CS-AuNPs were characterized by UV-vis absorption spectroscopy, transmission electron microscopy (TEM), X-ray diffractograms (XRD), and Fourier transform infrared spectroscopy (FTIR).

View Article and Find Full Text PDF
Article Synopsis
  • * The composition of MSC-EVs varies based on the tissue source of the MSCs and the methods used for their culture and isolation, highlighting the need for careful selection of MSC sources and culture techniques.
  • * The review analyzes molecular characteristics of MSC-EVs from different tissues using public datasets and AI techniques, revealing distinct biological pathways linked to various sources like adipose, bone marrow, and umbilical MSCs, which is crucial for advancing their therapeutic applications.
View Article and Find Full Text PDF

Clinical translation of gene therapy has been challenging, due to limitations in current delivery vehicles such as traditional viral vectors. Herein, we report the use of gRNA:Cas9 ribonucleoprotein (RNP) complexes engineered extracellular vesicles (EVs) for gene therapy. By leveraging a novel high-throughput microfluidic droplet-based electroporation system (μDES), we achieved 10-fold enhancement of loading efficiency and more than 1000-fold increase in processing throughput on loading RNP complexes into EVs (RNP-EVs), compared with conventional bulk electroporation.

View Article and Find Full Text PDF

Hypoxia-ischemia (HI) is one of the most common causes of death and disability in neonates. Apoptosis contributes to HI development. Interleukin-11(IL-11) has been shown to protect mice from cerebral ischemia/reperfusion injury.

View Article and Find Full Text PDF

Fibroblast activation protein (FAP) is tumor-specific and plays an important role in tumorigenecity. However, agents against its enzymatic activity or extracellular presence were unsuccessful in the clinic for undefined reasons. Here we show that FAP expression is higher in advanced ovarian cancer and is only detected in invasive ovarian cancer cells.

View Article and Find Full Text PDF

Objective: To evaluate the orthopedic effect of presurgical nasoalveolar molding (PNAM) devices on the palatal deformities in unilateral complete cleft lip and palate (UCCLP) patients.

Methods: Three groups with 19 patients each were studied. All samples in groups A and B were non-syndromic UCCLP children.

View Article and Find Full Text PDF

Objective: To develop a HPLC quantitative method for determination of schisandrin, schisandrol B, schisantherin A, deoxyschisandrin and gamma-schisandrin in Fructus Schisandrae.

Method: A symmetry C18 column (4.6 mm x 250 mm, 5 microm) was used with methanol (A) and water (B) as mobile phases, in gradient elution.

View Article and Find Full Text PDF