Publications by authors named "Zulfa Hidayati"
World J Oncol
August 2024
Article Synopsis
- In Indonesia, early-onset colorectal cancer (EOCRC) occurs more frequently in those under 50, potentially linked to a higher incidence of Lynch syndrome (LS) among CRC patients.
- A study at Dr. Sardjito General Hospital examined 244 samples for mutations in KRAS and PIK3CA, finding significant associations between these mutations, microsatellite instability (MSI) status, and Lynch syndrome.
- Results indicated that KRAS mutations correlate with right-sided colorectal cancer and higher histology grades, while PIK3CA mutations link to female patients and lower tumor-infiltrating lymphocyte levels; however, neither mutation significantly impacted overall survival.
