Texture Perception and Chewing of Agar Gel by People with Different Sensitivity to Hardness.

Hardness is one of the dominant sensory characteristics of food. This study estimated the effect of sensitivity to hardness on the texture perception and chewing function using 2, 4, and 6% agar gels. Increasing the concentration of agar resulted in an increase in gel hardness and springiness, measured by texture profile analysis.

Effect of Carrot Callus Cells on the Mechanical, Rheological, and Sensory Properties of Hydrogels Based on Xanthan and Konjac Gums.

The study aims to develop a plant-based food gel with a unique texture using callus cells and a mixture of xanthan (X) and konjac (K) gums. The effect of encapsulation of carrot callus cells (0.1 and 0.

[Is resistance to disinfectants a mandatory feature of a hospital strain of causative agents of nosocomial purulent-septic infections?].

Aim: Evaluate resistance to working solutions of disinfectants by Staphylococcus haemolyticus and Klebsiella pneumoniae isolated from newborns and hospital environment objects of obstetric hospital during registration of group purulent-septic infections (PSI).

Materials And Methods: Analysis of 2 epidemic situations on PSI morbidity of newborns caused by S. haemolyticus and K.

[The characteristics of epidemic influenza A and B virus strains circulating in Russia during the 2007-2008 season].

In 2007-2008 in Russia, the epidemic upsurge of influenza morbidity was caused by the active circulation of influenza A(H1N1, A(H3N2), and B viruses. The center for Ecology and Epidemiology of Influenza studied 334 epidemic strains. The results of a comparative study of the svirus specificity of commercial test systems (AmpliSens Influenza virus A/B and AmpliSens Influenza virus A/H5N1) for the polymerase chain reaction diagnosis and virological assays, including virus isolation, revealed their high correlation, which confirms that they may be expensively used to monitor the circulation of influenza viruses in the Russian Federation.

[Natriuretic peptide--independent marker of cardiovascular diseases in patients with diabetes mellitus].

The review depicts the findings of the foreign and Ukrainian researches focused on high blood level of natriuretic peptide (NP), which possesses, by itself, the risk of cardiovascular diseases in patients with diabetes mellitus regardless of its stage.

[Structure-functional features of homologous domains of angiotensin-converting enzyme].

Somatic angiotensin-converting enzyme (ACE) consists of two homologous domains, each of them containing an active site. Differences in substrate specificities and affinity to inhibitors of the active sites of the two domains of bovine ACE are described. The ACE domains demonstrate different thermostability, and the reasons for this difference are analyzed.

[Sulfonylurea receptors and their interaction with glimepiride].

In the review, data are presented on glymepiride (amaril), a 3-d generation sulphanylamide. The drug interacts with receptors to sulphonylurea--SUR X, that are found only in B-cells of the pancreas, which fact has been shown to be associated with a higher secretion of insulin, an increased sensitivity of peripheral tissues to this hormone and with insulin-like extrapancreatic effects as well. Amaril does not affect SUR of the myocardium, myocytes of cerebral vessels and nervous cells.

[Effect of eprex in therapy of anemia of nephrogenic genesis in patients with chronic renal failure concurrent with diabetic glomerulosclerosis before hemodialysis].

Data are submitted of results of treatment of anemia of nephrogenic genesis in 44 patients with diabetes mellitus complicated by diabetic glomerulosclerosis and chronic renal failure (CRF). In the patients, blood count was determined together with the corpuscular volume, blood serum level of creatinine, total protein, trace elements (calcium, sodium, potassium), total cholesterin, and beta-lipoproteins (beta-LP). Two drug regimens were adopted: 21 patient received iron preparations, folic acid, cyanocobalamin, calcium preparations, those preparations to be employed to reduce blood level of creatinine, antihypertensives, and eprex, 1000 u.

Temperature-induced selective death of the C-domain within angiotensin-converting enzyme molecule.

Somatic angiotensin-converting enzyme (ACE) consists of two homologous domains, each domain bearing a catalytic site. Differential scanning calorimetry of the enzyme revealed two distinct thermal transitions with melting points at 55.3 and 70.

[Immunomodulating effect of berlithione in clean-up workers of the Chernobyl nuclear plant accident].

Effects of the antioxidant berlithione (alpha-lipoic acid) on indices for the immune system, such as complement titer, C3-component of the complement, reaction of the autorosette formation were studied together with those on parameters characterizing cell-bound and humoral immunity. 11-12 years following the Chernobyl accident, nine liquidators of its aftermaths were examined, aged 51.8 +/- 7.

[Hyperinsulinemia as a factor preceding body mass increase in liquidators of the Chernobyl nuclear accident].

Basal hyperinsulinemia has been recordable over several years in liquidators of the effects of Chernobyl Accident (ChAEL). There was no dependence of hyperinsulinemia on age, body mass or lenght of service of those persons having worked within the 30-km zone. The findings secured suggest to us that increase in the body mass index (BMI) in ChAEL is preceded by a rise in the blood level of insulin; there is no relatedness of the basal level of insulin in the blood to BMI.

[Analysis of irradiation dose, body mass index and insulin blood concentration in personnel cleaning up after the Chernobyl nuclear plant accident].

Liquidators of aftermaths of the Chernobyl accident (LCA) who had worked within the 30-km zone for not more then 3 months in 1986 and early in the year 1987 were examined in 1988-1992, 1997-1998. They were divided into two groups of persons with normal body mass index (BMI) and abnormal BMI. The dose of irradiation received, BMI and insulin concentration in the blood were analysed.

[Ceruloplasmin, transferrin and insulin blood levels in those with diabetes mellitus type II and in nondiabetics who participated in the clean-up after the Chernobyl accident].

In those persons who had taken part in the elimination of the effects of the Chernobyl accident (AEEP), an oxidative stress with disturbed functioning of the antioxidant defence extracellular factors ceruloplasmin and transferrin is recordable over a long time range together with direct and indirect manifestations of insulin resistance. Submitted in the paper is an analysis of indices for ceruloplasmin, transferrin, free iron (FI), and insulin in the blood plasma of AEEP in different age groups and in those AEEP suffering from type II diabetes mellitus (DM) as well. The group of comparison was participants in the military operations (MOP) in Afghanistan.

[The results of monitoring enterovirus circulation circulation among the population and in the environment of Tula Province over 10 years (1985-1994)].

The study of the isolation rate of polioviruses and other enteroviruses in patients with different diagnosed diseases, among healthy child population, as well as the circulation of these viruses in the environment was carried out on the territory of Tula Province for the period of 1985-1994. The epidemiological analysis of the data obtained in this study are presented. The study revealed that the vaccinal prophylaxis of poliomyelitis, carried out for the period of many years, did not lead to the elimination of poliovirus strains, differing in their genetic properties from vaccine strains, on the territory of Tula Province.

[The adaptation of the human central nervous system to ecological job factors].

The EEG, quantity of cation proteins in neutrophils, the opioid peptides concentration in the CSF, were analysed in military personnel after a prolonged climatic and specific stress complicated by traumas, at the Kabul military hospital in Afghanistan. The brain functional reserve was significantly lower in the control subjects. A positive correlation between the brain functional reserve and the average cytochemical coefficient, was found in certain phases of traumatic disease alone.

[Properties, production, and practical uses of alkaline phosphatase].

Literary data concerning the properties, isolation, purification and practical applications of alkaline phosphatase isolated from different sources are reviewed with special reference to the macromolecular structure and action mechanism of the enzyme in the reactions of phosphomonoester hydrolysis. The practicality of alkaline phosphatase as a helpful tool in conducting enzyme-linked immunoassays is demonstrated.

[Structural effects in the sarcolemma of the cardiomyocytes under the action of modulators of the polyphosphoinositide system].

The influence of activators (Ca(2+)-channels stimulator BAY K 8644 and phospholipase C stimulator fMLP) and inhibitors (Ca(2+)-channels blocker verapamil and alpha 1-adrenoceptors blocker prazosin) of the polyphosphoinositide system on cardiomyocytes sarcolemma, was studied. The structural effects of the PPI modifiers seem to be one of the mechanisms of the PPI physiological activity at the membrane level.

[The effect of composition and ionic strength of external solution on the aspartate-ammonia lyase and fumarate hydratase activity in Escherichia coli cells].

It was found that the nonspecific effect of ionic strength of the external solution on the enzymatic activity of E. coli cells consists in rapid changes in the permeability of cell membranes interacting with the substrate. This effect depends on the initial substrate concentration, i.

[Determination of 3,4-dioxyphenyl-L-alanine by spectrophotometric and chromatographic methods in enzymatic synthesis using microbial cells].

A possibility of using the ninhydrin reaction for 3,4-dihydroxyphenyl-L-alanine (DOPA) determining during the synthesis from pyrocatechol and ammonium pyruvate was verified by using free and immobilized cells of Citrobacter freundii, st. 62. Spectrophotometric assay was performed at the adsorption maximum for the DOPA-ninhydrin complex at 390 nm.

[Enzymatic synthesis of L-malic acid from fumaric acid using immobilized Escherichia coli cells].

Optimal conditions were chosen for cultivation of Escherichia coli 85 cells with a rather high fumarate-hydratase activity on a cheap medium containing no edible raw material. An active biocatalyst for the synthesis of L-malic acid from fumaric acid was obtained based on E. coli 85 cells immobilized in carrageenan.

[Kinetic study of 3,4-dihydroxyphenyl-L-alanine synthesis in Citrobacter freundii cells immobilized in carrageenan].

A kinetic study was carried out of the enzymatic synthesis of 3,4-dihydroxyphenyl-L-alanine (DOPA) by the Citrobacter freundii 62 cells, possessing tyrosine-phenol-lyase (TPL) activity, immobilized in carrageenan, and optimum conditions of the reaction were found. The dependence of the TPL activity and its stability on the conditions of the DOPA synthesis was investigated. The TPL activity was higher and more stable in the immobilized cells as compared to free ones.