Background: Idiopathic intracranial hypertension (IIH) is characterized by increased cerebrospinal fluid (CSF) pressure of unknown cause. It has been suggested that the inflammatory process plays a role in the pathophysiology of the disease. Sortilin-1, lipocalin-2, autotaxin, decorin, and interleukin-33 (IL-33) are among the factors involved in inflammatory processes.
View Article and Find Full Text PDFBackground: Migraines are headaches caused by changes in the trigeminovascular metabolic pathway. Migraine headache attacks are associated with neurovascular inflammation, but their pathophysiological mechanisms have not been fully explained.
Objective: To investigate the relationship between serum vaspin, visfatin, chemerin and interleukin-18 (IL-18) levels and the frequency of attacks in migraine headache.
Objective: Many cardiovascular complications, including hypertension, are seen in pediatric liver transplantation. The purpose of this study was to analyze the frequency of arterial hypertension of pediatric liver transplant recipients and also to determine the related risk factors.
Methods: Thirty-six pediatric liver transplant recipients aged 8-17 years were prospectively studied by manual and ambulatory blood pressure measurement (ABPM) technique.
Arq Neuropsiquiatr
October 2020
Background: YouTube is one of the major resources for health related videos around the world.
Objective: The aim of this study was to evaluate the quality of information available on YouTube about restless leg syndrome (RLS).
Methods: A YouTube search was carried out on https://www.
Background: Intra-arterial injection of medications may cause acute and severe ischemia and result in morbidity and mortality. There is no information in the literature evaluating the arterial endothelial effects of sugammadex and dexmedetomidine. The hypothesis of our study is that sugammadex and dexmedetomidine will cause histological changes in arterial endothelial structure when administered intra-arterially.
View Article and Find Full Text PDFBackground: Intra-arterial injection of medications may cause acute and severe ischemia and result in morbidity and mortality. There is no information in the literature evaluating the arterial endothelial effects of sugammadex and dexmedetomidine. The hypothesis of our study is that sugammadex and dexmedetomidine will cause histological changes in arterial endothelial structure when administered intra-arterially.
View Article and Find Full Text PDFObjective: The objectives of this study were to investigate the relationship between the segmental localization of liver hydatid cyst by computed tomography (CT) and the presence of cystobiliary communication (CBC) and to identify the risk factors for CBC.
Patients And Methods: One hundred and eleven of 163 patients who underwent liver hydatid surgery between January 2011 and September 2014 were included in this study and analyzed retrospectively. The size, number, stage, and segmental and lobar localization of the cysts were investigated by CT.
Purpose: To investigate the therapeutic effects of ellagic acid on L-arginin ınduced acute pancreatitis in rats.
Methods: Thirty-two were split into four groups. Group 1 (control) rats were performed only laparotomy, no drugs were administered.
Background: The purpose of our study was to share our experience in patients with traumatic diaphragmatic rupture.
Methods: Patients underwent surgery for traumatic diaphragm rupture between 2005 and 2010 were reviewed.
Results: There were sixty-two patients with traumatic diaphragm rupture.
Aim: Inflammation may be involved in the ictogenesis and development of some partial epilepsies. Serum albumin levels and the neutrophil-lymphocyte ratio (NLR) are markers of inflammation. The aim of this study was to investigate the ability of serum albumin levels and NLR to predict inflammation in patients with convulsive status epilepticus (CSE).
View Article and Find Full Text PDFEur Rev Med Pharmacol Sci
October 2016
Objective: We aimed to investigate the protective potential of pomegranate extract on the liver and remote organs in rats with obstructive jaundice.
Materials And Methods: The rats were split into 4 groups. In Group 1 (G1) (sham group) rats, the common bile duct was mobilized without any ligation.
Acta Chir Belg
February 2016
Background: To determine the effect of thymoquinone on adhesion formation in a rat caecotomy/suture model.
Material And Methods: Thirty wistar rats were randomized into three groups: The control group received saline and the thymoquinone group received 10 mg/kg thymoquinone after cecal caecotomy/suture model. In the sham group the abdominal wall was closed without any abrasion to the cecum.
Eur Rev Med Pharmacol Sci
June 2015
Objective: Humans and other animals are liable to expose to low doses of malathion (MAL). However, experimental studies on its toxic threshold dose and toxic low-dose effects have not been conducted. The aims of this study were to detect the initiation of the toxic effects of sub-acute low doses (2.
View Article and Find Full Text PDFLiposarcomas are one of the most common primary lesions of the retroperitoneal region. They rarely exhibit intra-abdominal location. Because the symptoms emerge later on, they often remain unnoticed until they grow large.
View Article and Find Full Text PDFXanthogranulomatous cholecystitis is a rare variant of chronic cholecystitis characterized by severe proliferative fibrosis and accumulation of lipid-laden macrophages in regions of destructive inflammation. Xanthogranulomatous cholecystitis clinically and radiologically mimics early-stage gallbladder cancer, with wall thickening on computed tomography. The study included 14 xanthogranulomatous cholecystitis patients that were identified following retrospective analysis of the records of 1248 patients that underwent cholecystectomy between 2005 and 2011.
View Article and Find Full Text PDFBackground: Rectovaginal fistula is an epithelial connection between the anterior wall of the rectum and posterior wall of the vagina. The etiology of the rectovaginal fistula can be trauma orginated from violent acts or foreign bodies as well as trauma during obstetric, gynecologic, or colorectal surgeries. The purpose of this study was to share our clinic experience and surgical management for rectovaginal fistulas.
View Article and Find Full Text PDFIntroduction: Obstruction of the common bile duct is associated with hepatic paranchymal damage and increased susceptibility to subsequent bacterial infections. Erythropoietin has antiinflammatory and cytoprotective effects and it induces antiinflammatory cytokines and suppresses the production of proinflammatory cytokines. In this study, we aimed to investigate the effect of Erythropoietin on bacterial translocation, inflammation and tissue damage in rats with obstructive jaundice.
View Article and Find Full Text PDFJ Neurol Surg A Cent Eur Neurosurg
January 2015
Purpose: To examine the effect of intrathecally given caffeic acid phenethyl ester (CAPE) on peroxidation and total oxidant and antioxidant systems, and the effect of intrathecally given methylprednisolone (MP) in spinal cord injury (SCI) models.
Materials And Methods: Four groups of 10 rats were formed: (1) Laminectomy, intrathecal saline injection, no SCI (sham: S); (2) Laminectomy, intrathecal saline injection, SCI (control: SCI); (3) Laminectomy, intrathecally given single dose of 3 mg/kg MP, SCISCI (SCI + MP). 4) Laminectomy, intrathecally given single dose of 1 µg/kg CAPE, SCI (SCI + CAPE).
Background And Aim: Hollow visceral injuries following blunt abdominal trauma are uncommon. The potential risk factors affecting morbidity and mortality are not well known. The purpose of our study was to evaluate the outcomes of hollow viscus perforation after blunt abdominal trauma.
View Article and Find Full Text PDFEur Rev Med Pharmacol Sci
October 2013
Background: The aim of this experimental study was to compare the safety of different suture materials in a left colonic anastomosis in the presence of peritonitis.
Materials And Methods: Twenty-one male Wistar albino rats were randomly divided into three groups. First, left colonic injuries were created in all groups for the peritonitis model.
Adult intussusception is an uncommon disease requiring surgical intervention. The aim of this study is to discuss the surgical alternatives and share our experience in the treatment of adult patients with intussusceptions formed as a result of polyps. The retrospective study included 16 adult patients who underwent surgery after the diagnosis of intestinal invaginations resulting from polyps between the years 2000 and 2011.
View Article and Find Full Text PDFThere are limited studies evaluating the fibrinogen levels in patients with migraine. It remains unknown whether the levels of the haematological marker of thromboembolism, D-dimer, and the levels of galectin-3, which plays an important role in inflammation as a proinflammatory mediator, change during the attacks in patients with migraine. The present study aims to compare galectin-3, fibrinogen and D-dimer levels in patients with migraine during the attacks and interictal periods, and to compare galectin-3, fibrinogen and D-dimer levels between patients with migraine and healthy controls to investigate the role of these parameters in the pathogenesis of migraine.
View Article and Find Full Text PDFBackground: Pancreatic injuries arising from blunt trauma are rarely seen. Diagnosis and treatment are difficult because of retroperitoneal localization of the organ. We present four pancreatic cases with isolated pancreatic injury due to blunt abdominal trauma.
View Article and Find Full Text PDFMigraine is a type of primary headache which is caused by the alterations in trigeminovascular system. Migraine attacks are associated with neurovascular inflammation of the cerebral and extracerebral vessels, but its pathophysiological mechanisms have not still been fully delineated. Also, migraine has been found to be associated with higher risks for various metabolic disorders.
View Article and Find Full Text PDFEur Rev Med Pharmacol Sci
July 2013
Background And Objectives: The relationship of the mean platelet volume (MPV) and C-reactive protein (CRP) values with mortality in patients with ischemic stroke is not clear. Besides, the correlation between CRP and MPV in patients with ischemic stroke has not been adequately studied yet. In the present study, our aim is to investigate the interrelationship of the CRP and MPV parameters together with their influence on mortality in patients with acute ischemic stroke.
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