Publications by authors named "Zuehre Ikiz"

Optimal brain health is essential to smoothing major global skill-intensive economic transitions, such as the bioeconomy, green, care economy and digital transitions. Good brain health is vital to socio-economic sustainability, productivity and well-being. The care transition focuses on recognizing and investing in care services and care work as essential for economic growth and social well-being.

View Article and Find Full Text PDF
Article Synopsis
  • Aging leads to a decline in thermoregulation, lowering core body temperature (Tc), which, while being a marker of healthy aging, negatively affects cognitive function in Alzheimer's disease models.
  • The study tested whether increasing Tc through thermotherapy could enhance metabolism and cognitive performance in APP/PS1 mice by exposing them to higher temperatures (30°C) compared to standard conditions (23°C) from 6 to 12 months of age.
  • Results showed improved glucose tolerance and insulin sensitivity in mice exposed to higher temperatures, with varying effects based on sex; while male mice benefited cognitively, female APP/PS1 mice experienced worsened spatial memory, highlighting the need for more research on thermotherapy's potential
View Article and Find Full Text PDF

This study presents the first definitive confirmation of microplastic presence in the human stomach, based on samples from 26 cadavers. 97 microplastic particles were extracted from stomach contents, across all 26 individuals, revealing a universal prevalence of microplastics in the cadavers. Morphological analysis of the extracted particles unveiled distinct shapes, with fibers constituting the majority (52.

View Article and Find Full Text PDF

Backround: The utilization of high-quality water in agriculture is increasingly constrained by climate change, affecting availability, quality, and distribution due to altered precipitation patterns, increased evaporation, extreme weather events, and rising salinity levels. Salinity significantly challenges salt-sensitive vegetables like lettuce, particularly in a greenhouse. Hydroponics water quality ensures nutrient solution stability, enhances nutrient uptake, prevents contamination, regulates pH and electrical conductivity, and maintains system components.

View Article and Find Full Text PDF

Tumor deposits (TDs) are defined as discontinuous neoplastic masses within the lymphatic drainage pathway of the primary tumor. The poor prognostic implication of these masses have been demonstrated in various cancers. The aim of this study is to investigate the incidence of TDs in our thyroid carcinoma cases, which has not been studied so far to the best of our knowledge, and to determine the prognostic value of their existence.

View Article and Find Full Text PDF

Microglia are the resident macrophages of the central nervous system (CNS) that control brain development, maintain neural environments, respond to injuries, and regulate neuroinflammation. Despite their significant impact on various physiological and pathological processes across mammalian biology, there remains a notable gap in our understanding of how microglia perceive and transmit mechanical signals in both normal and diseased states. Recent studies have revealed that microglia possess the ability to detect changes in the mechanical properties of their environment, such as alterations in stiffness or pressure.

View Article and Find Full Text PDF

This NeuroView assesses the interplay among exposome, One Health, and brain capital in health and disease. Physical and social exposomes affect brain health, and green brain skills are required for environmental health strategies. Ibanez et al.

View Article and Find Full Text PDF

This study, which included patients over the age of 18 who were diagnosed with coronavirus disease 2019 (COVID-19) in the emergency clinic, aims to determine the relationship between coagulation parameters and mortality. Epidemiologic data such as age, gender, medical history, vital parameters at emergency department admission, clinical findings, coagulation parameters such as d-dimer, prothrombin time (PT), active partial thromboplastin time (aPTT), international normalized ration (INR), fibrinogen, and platelet were evaluated. Patients with positive computerized tomography (CT) findings and positive polymerase chain reaction (PCR) together were included in the study.

View Article and Find Full Text PDF

A thermoregulatory decline occurs with age due to changes in muscle mass, vasoconstriction, and metabolism that lowers core body temperature (Tc). Although lower Tc is a biomarker of successful aging, we have previously shown this worsens cognitive performance in the APP/PS1 mouse model of Alzheimer's disease (AD) [1]. We hypothesized that elevating Tc with thermotherapy would improve metabolism and cognition in APP/PS1 mice.

View Article and Find Full Text PDF

Background: The burnout rates among residents urge for adequate interventions to improve resilience and prevent burnout. Peer reflection, also called group intervision sessions, is a potentially successful intervention to increase the resilience of young doctors. We aimed to gain insight into the perceived added value of intervision sessions and the prerequisite conditions to achieve this, according to residents and intervisors.

View Article and Find Full Text PDF

In soilless cultivation, plants are grown with nutrient solutions prepared with mineral nutrients. Beneficial microorganisms are very important in plant nutrition. However, they are not present in soilless culture systems.

View Article and Find Full Text PDF

Objective: The aim of the study was to retrospectively analyze the patients who underwent thyroidectomy at a tertiary academic center regarding their surgical indications, histopathological diagnosis, and surgical complications.

Methods: The study included a total of 739 consecutive patients who underwent lobectomy, total thyroidectomy, or completion thyroidectomy performed under intraoperative nerve monitoring (IONM) at the Department of Otorhinolaryngology-Head and Neck Surgery of Dokuz Eylül University between January 2009 and December 2019. Demographic data of the patients, preoperative clinicopathological characteristics, postoperative complications, characteristics of surgery and histopathological results were evaluated.

View Article and Find Full Text PDF

The fermented liquid sector is developing all over the world due to its contribution to health. Our study has contributed to the debate about whether industrially manufactured fermented liquids live up to their claims by analyzing pathogens and beneficial bacteria using a 16S rRNA sequencing technique called metagenomic analysis. , , , , , and were the most abundant bacterial genera observed as potential probiotics.

View Article and Find Full Text PDF

Background: In the literature, the efficacy of virtual glasses on acute pain and anxiety has been investigated, and no study has been found on its effect on pain and anxiety during episiotomy repair.

Aims: To determine the efficacy of virtual glasses application in pain and anxiety during episiotomy repair.

Design: Randomized controlled trial design was used.

View Article and Find Full Text PDF
Article Synopsis
  • Anti-tumor necrosis factor agents are commonly used to treat ankylosing spondylitis.
  • These medications can lower the immune response, raising the risk of infections in patients.
  • Physicians need to monitor patients closely for any signs of recurrent infections while they are on these treatments.
View Article and Find Full Text PDF

Background: Dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) can in vivo characterize tumor microvascular environment. The aim of the present study was to reveal the DCE-MRI findings and to determine the correlation between these findings and immunohistochemical data in head and neck squamous cell carcinoma (HNSCC).

Methods: Thirty-three patients diagnosed with primary HNSCC were evaluated retrospectively.

View Article and Find Full Text PDF

Hydroponics is one of the systems in agriculture which reinforce productivity by controlling environmental and growing conditions. In this study, we evaluated the effect of three bio-fertilizers, namely bacteria, micro-algae, and mycorrhiza, on basil leaf yield and quality (Ocimum basilicum L.) in a floating culture system.

View Article and Find Full Text PDF

Background:  Cochlear implants (CIs) improve spoken language skills as well as social and academic performance in children with severe and profound sensorineural hearing loss.

Purpose:  We compare the social skills, academic competence, and problem behaviors in children with CIs and their typical-hearing peers and investigate the relationship between language skills and social skills, academic competence, and problem behaviors in children with CIs.

Research Design:  Thirty-two children with CIs were divided into two groups according to implantation age: early ( = 17) and late-implanted group ( = 15).

View Article and Find Full Text PDF

Objective: Hearing loss is associated with reduced quality and quantity of auditory input, and difficulty in cognitive and language skills. This study aimed to investigate the relationship between language, working memory, and rapid naming skills in children with mild to moderate sensorineural hearing loss (MMHL).

Methods: Twenty children with MMHL with the same auditory experience and demographical conditions using bilateral hearing aids were included.

View Article and Find Full Text PDF

This study aimed to determine the relationship between musculoskeletal problems in office workers and their physical activity levels and quality of life. A questionnaire form, the quality of life scale (SF-36) and the international physical activity questionnaire (IPAQ) were used. Group differences were compared post hoc (Bonferroni) and non-parametrically (Mann-Whitney test, etc.

View Article and Find Full Text PDF

Background: Intestinal ischemia causes an inflammatory response that may become intense by reperfusion and result in bacterial translocation. Intestinal immunoglobulin A is known to be a barrier against bacterial translocation. Lycopene is a compound with antioxidant and anti-inflammatory properties.

View Article and Find Full Text PDF

Objective: This study aimed to evaluate the effects of adding different doses of remifentanil to propofol treatment compared with propofol alone with regard to parameters, including the seizure duration, haemodynamic changes and recovery time, in patients undergoing electroconvulsive therapy (ECT).

Methods: This study was designed as a self-controlled, prospective, double-blind investigation of 17 patients between the ages of 20 and 65 years who had planned treatment with ECT at a psychiatric clinic. Group P (propofol) was administered 10 mL of normal saline after 0.

View Article and Find Full Text PDF

Objectives: Radioiodine can be applied for remnant ablation in low and low to intermediate-risk patients with differentiated thyroid cancer (DTC). A controversy still exists about the application time interval of radioiodine following total thyroidectomy. In this study, we investigated the effect of radioiodine (RAI) therapy timing on the success rates of the ablation.

View Article and Find Full Text PDF

Cell-to-cell communications are critical determinants of pathophysiological phenotypes, but methodologies for their systematic elucidation are lacking. Herein, we propose an approach for the Systematic Elucidation and Assessment of Regulatory Cell-to-cell Interaction Networks (SEARCHIN) to identify ligand-mediated interactions between distinct cellular compartments. To test this approach, we selected a model of amyotrophic lateral sclerosis (ALS), in which astrocytes expressing mutant superoxide dismutase-1 (mutSOD1) kill wild-type motor neurons (MNs) by an unknown mechanism.

View Article and Find Full Text PDF