Publications by authors named "Zucheng Shang"
Article Synopsis
- Dehydrocorydaline (DHC), an active component of a plant used in traditional medicine, shows promise in treating coronary heart disease due to its protective and pain-relieving effects, though the mechanism is not fully understood.
- The study aimed to investigate whether DHC can mitigate myocardial ischemia-reperfusion injury (MIRI) by affecting the FoxO signaling pathway to reduce cell death (apoptosis).
- Experimental results demonstrated that DHC improved heart function in a mouse model of MIRI and reduced apoptosis and oxidative stress in heart cells exposed to hypoxia, principally through the FoxO pathway.
Baicalin, a flavonoid glycoside from Scutellaria baicalensis Georgi., exerts anti-hypertensive effects. The present study aimed to assess the cardioprotective role of baicalin and explore its potential mechanisms.
View Article and Find Full Text PDFAs a main extraction compound from Scutellaria baicalensis Georgi, Baicalin exhibits various biological activities. However, the underlying mechanism of Baicalin on hypertension-induced heart injury remains unclear. In vivo, mice were infused with angiotensin II (Ang II; 500 ng/kg/min) or saline using osmotic pumps, followed by intragastrically administrated with Baicalin (5 mg/kg/day) for 4 weeks.
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