Publications by authors named "Zuchen Sun"
Diabetes is characterized by elevated levels of blood glucose, which can result in the modification of serum proteins. The modification of a protein by glucose, or glycation, can also lead to the formation of advanced glycated end-products (AGEs). One protein that can be modified through glycation and AGE formation is human serum albumin (HSA).
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- Many biological processes depend on how solutes interact with proteins and compete for binding.
- Zonal elution affinity chromatography is a method developed to study these interactions, focusing on solute-protein binding, solute-solute competition, and the overall strength of these interactions.
- This technique also has diverse applications, including analyzing solute binding in different solvents and temperatures, characterizing protein binding sites, and combining immunoextraction for drug-protein binding studies.