Plasma homocysteine levels and the left ventricular systolic function in coronary artery disease patients.

Background: Numerous studies have shown a relationship between hyperhomocysteinemia, atherothrombosis and cardiovascular mortality. However, an association between hyperhomocysteinemia and the extent of coronary artery disease (CAD) remains controversial whereas its relationship with left ventricular systolic function has not been established.

Methods: One hundred and fifty-seven patients with angiographically defined CAD were included.