Synopsis of recent research by authors named "Zu-feng Guo"
Zu-feng Guo's research focuses on the biochemical mechanisms and interactions of antimalarial drugs, particularly artemisinins, exploring their effects on redox processes within malaria parasites and their interactions with other drugs like methylene blue and chloroquine.
His studies have demonstrated that artemisinins impact redox homeostasis in malaria parasites by oxidizing key cofactors, leading to the generation of reactive oxygen species, which is central to their antimalarial activity.
In addition to antimalarial research, Guo has investigated the biosynthetic pathways of menaquinone in Escherichia coli, examining enzyme mechanisms and the effects of various ligands and cofactors on enzyme activity.
