Cost-Effectiveness analysis of combining plasma Epstein-Barr virus DNA testing and different surveillance imaging modalities for nasopharyngeal carcinoma patients in first remission.

Background: To evaluate the cost-effectiveness of stage-based post-radiotherapy (PRT) nasopharyngeal carcinoma (NPC) surveillance strategies.

Methods: Four post-radiotherapy surveillance strategies were established by a Markov model based on data from 1664 patients: 1) clinical follow-up (CFP) with biannual Epstein-Barr virus (EBV) DNA (EBV DNA strategy); 2) CFP with biannual EBV DNA, annual head and neck magnetic resonance imaging (HNMRI), chest X-ray, abdominal ultrasonography, bone scan (only for the first two years) for five years (MCWU strategy); 3) CFP with biannual EBV DNA, annual HNMRI, chest, abdomen, pelvic computerized tomography (CT) and bone scan for the first two years, followed by annual MCWU strategy (without bone scans) for the last three years (CT strategy); 4) CFP with biannual EBV DNA, annual whole-body positron emission/computerized tomography (PET/CT) for the first two years and biannual EBV DNA for the last three years (PET/CT strategy).

Results: Compared with the EBV DNA strategy, the MCWU, CT, and PET/CT strategies gained 0.

Evaluation of Need and Distribution of National Essential Medicines List in Village Clinics: A Cross-sectional Study Based on the Perspective of Village Doctors in China.

This study aimed to evaluate the satisfaction of village doctors to essential medicines list (EML) and accessibility of essential medicines (EMs) distribution to improve the implementation of EML in village clinics. A total of 422 village doctors from five counties in three provinces of China were surveyed by questionnaires. Logistic regression analysis was conducted to identify the main factors associated with village doctors' evaluation of EML.

Acute stroke patients' knowledge of stroke at discharge in China: a cross-sectional study.

Objectives: A good mastery of stroke-related knowledge can be of great benefit in developing healthy behaviours. This study surveyed the knowledge about stroke and influencing factors among patients with acute ischaemic stroke (AIS) at discharge in a Chinese province.

Methods: A cross-section study was conducted from November 1, 2014 to January 31, 2015.

Chinese neurologists' perspective on intravenous thrombolysis for acute ischemic stroke.

Objectives: This study examined the neurologists' perspective toward intravenous thrombolysis for the treatment of acute ischemic stroke and the influencing factors in a Chinese Province.

Methods: A cross-sectional study was conducted from 1 October 2014 to 31 January 2015. A total of 719 neurologists from 66 hospitals in Hubei Province were included.

Factors Affecting Patient Satisfaction with Community Health Service under the Gatekeeper System: A Cross-sectional Study in Nanjing, China.

The gatekeeper policy has been implemented for approximately ten years on a pilot population in China. It is necessary to assess the satisfaction of patients utilizing community health service (CHS) under the gatekeeper system. Our study showed that the cognition of gatekeeper policy was associated with four dimensions including doctor-patient relationships, information and support, organization of care, and accessibility (P < 0.

Depression and the risk of breast cancer: a meta-analysis of cohort studies.

Background: Whether depression causes increased risk of the development of breast cancer has long been debated. We conducted an updated meta-analysis of cohort studies to assess the association between depression and risk of breast cancer.

Materials And Methods: Relevant literature was searched from Medline, Embase, Web of Science (up to April 2014) as well as manual searches of reference lists of selected publications.

[Evaluation of effects of combination intervention model to men who have sex with men].

Objective: This study aimed to explore and evaluate the effects of combination intervention model conducted by Center for Disease Control and Prevention and activity place to men who have sex with men (MSM).

Methods: To implement one-year combination intervention in 4 MSM venues during May, 2009 and April, 2010. Meanwhile, 3 similar MSM venues were chosen as control.

[Comparative study of the factors in tuberculosis treatment between immigrant workers and local residents in Shenzhen].

Objective: To study the factors affecting the management and treatment of immigrant workers with tuberculosis, to determine the most effective measures and to provide an academic basis for tuberculosis control and prevention strategies targeting the immigrant population.

Methods: A self-designed questionnaire was administered to 1364 immigrant workers with tuberculosis (study group) and 436 local residents (control group) with tuberculosis.

Results: Whether a patient's tuberculosis status was discovered or not was related to the medical facilities initially visited, job mobility, and the individual worker's economic condition.

[Study on the relationship between polymorphisms of XPA gene and susceptibility of esophageal cancer].

Objective: To explore the relationships between the polymorphisms of xeroderma pigmentosum A (XPA) and the susceptibility of esophageal cancer (EC), as well as its interaction with environmental factors-gene in Changzhi area, Shanxi province.

Methods: A case-control study was conducted, including 196 cases of EC and 201 controls. XPA 23G polymorphisms were determined with polymerase chain-restriction on fragment length polymorphism (PCR-RFLP).

[An assessment on the effectiveness of condom use in reducing the incidence of chlamydia through mathematical modelling].

Objective: To determine the relationship between the rate of condom use and incidence of Chlamydia amongst commercial sex worker, using a mathematical model.

Methods: Assuming that p(%) is the rate of condom use by female sex workers, and r(%) is the incidence of Chlamydia. If the use of condom increases by delta p, then the incidence of Chlamydia will decrease by delta r.

[Prospective study on family burden following traumatic brain injury in children].

Objective: To collect basic information on family burdens and long-term influence of children suffered from traumatic brain injury (TBI).

Methods: Through prospective study, child behavioral problems, and injury-related family burden were assessed longitudinally in children with TBI over 6 months during the post injury period and children's pre-injury family function rated by parents soon after injury. Post injury child behavior and family outcomes were assessed at 6-month follow-up period.

[Study on the relations between serum insulin-like growth factor-1, insulin-like growth factor binding protein-3 and colorectal cancer: a meta-analysis].

Objective: To evaluate the relationship between circulating levels of insulin-like growth factor-1 (IGF-1), IGF-binding protein-3 (IGFBP-3) and colorectal cancer.

Methods: A meta-analysis of 6 epidemiological studies on insulin-like growth factors and risk of colorectal cancer were performed.

Results: The pooled odds ratio (OR) of IGF-1 and IGFBP-3 were 1.