ESR1 Gene Polymorphisms and Prostate Cancer Risk: A HuGE Review and Meta-Analysis.

Background: Many published data on the association between single nucleotide polymorphisms (SNPs) in the ESR1 gene and prostate cancer susceptibility are inconclusive. The aim of this Human Genome Epidemiology (HuGE) review and meta-analysis is to derive a more precise estimation of this relationship.

Methods: A literature search of PubMed, Embase, Web of Science and Chinese Biomedical (CBM) databases was conducted from their inception through July 1st, 2012.

Efficacy and tolerability of oxycodone in moderate-severe cancer-related pain: A meta-analysis of randomized controlled trials.

In order to evaluate the efficacy and tolerability of oxycodone in moderate-severe cancer-related pain, we conducted a systematic review of randomized controlled trials (RCTs). Publications addressing the efficacy and tolerability of oxycodone in moderate-severe cancer-related pain were selected from the Cochrane library, PubMed, Embase and CBM databases. Data were extracted from the studies by two independent reviewers.

[Design of a flyback switch mode power supply for multichannel electrophysiological stimulators].

In order to supply the multichannel electrical stimulator, a DC-DC flyback switch mode power supply based on a high-performance current mode controller UC3845 has been designed. The experimental results indicate that the power supply has satisfied the demands and can supply the multichannel electrical stimulator and similar apparatuses.

[Design of a wireless fetal electrocardiogram monitoring system based on S3C2410].

This paper introduces a new fetal electrocardiogram monitoring system based on S3C2410 and telecommunication, and its framework and flow chart. Based on the genetic algorithm, the improved IIR adaptive filter achieves the non-invasive, real-time extraction of FECG. The system provides the reliable gist for the diagnosis of fetal congenital diseases.