Arachidonate lipoxygenases 5 is a novel prognostic biomarker and correlates with high tumor immune infiltration in low-grade glioma.

To investigate the prognostic value of arachidonate lipoxygenases 5 (ALOX5) expression and methylation, and explore the immune functions of arachidonate lipoxygenases 5 expression in low-grade glioma (LGG). Using efficient bioinformatics approaches, the differential expression of arachidonate lipoxygenases 5 and the association of its expression with clinicopathological characteristics were evaluated. Then, we analyzed the prognostic significance of arachidonate lipoxygenases 5 expression and its methylation level followed by immune cell infiltration analysis.

Resident Microglia Activate before Peripheral Monocyte Infiltration and p75NTR Blockade Reduces Microglial Activation and Early Brain Injury after Subarachnoid Hemorrhage.

Early brain injury (EBI) after aneurysmal subarachnoid hemorrhage (SAH) contributes to high morbidity and mortality. Although it is well recognized that acute neuroinflammation reaction is one of the most important triggers of EBI, pharmacotherapy proved to be clinically effective against the initiating of neuroinflammation after SAH is lacking. The resident microglia and infiltrated peripheral monocyte are two main types of immune cells in central nervous system (CNS) and control the inflammation process in brain after SAH.

[Treatment of Idiopathic Normal-Pressure Hydrocephalus by Wuling Powder Combined Ventriculo- peritoneal Shunt Surgery: an Efficacy Observation].

Objective To observe the clinical efficacy of Wuling Powder (WP) combined ventricu- loperitoneal shunt surgery in patients with idiopathic normal-pressure hydrocephalus (INPH). Methods Totally 56 INPH patients were randomly assigned to the control group and the treatment group, 28 in each group. All patients received ventriculoperitoneal shunt surgery.

Enhancement of the Photocatalytic Activity of Carbon Nitrides by Complex Templating.

Carbon nitrides with the increased surface areas (≈90 m(2) g(-1)) were prepared by the heat-treatment of melamine-[Al(NO3)3]⋅9 H2O complexes. Here, [Al(NO3)3]⋅9 H2O was successfully used as a "green template" and a hydrogen-bonding partner of melamine, simultaneously providing a distinct porosity and defined particle morphology for the resulting carbon nitrides. The influence of the solvent and precursors ratio on the stoichiometry of the complexes, as well as the morphology, optical properties, and photocatalytic activity of resulting products for Rhodamine B degradation and sacrificial hydrogen evolution were investigated.

Microcontact-printing-assisted access of graphitic carbon nitride films with favorable textures toward photoelectrochemical application.

An "ink" (cyanamide) infiltrated anodic aluminum oxide (AAO) stamp is found capable of printing carbon nitride films featuring regular microstructures of the stamp onto the substrates via in situ "chemical vapor deposition". A photocurrent density of 30.2 μA cm(-2 --) at 1.

The bioinspired construction of an ordered carbon nitride array for photocatalytic mediated enzymatic reduction.

A carbon nitride array (CNA) material has been constructed using a sacrificial diatom template. A regular carbon nitride nanorod array could be replicated from the periodic and regular nanochannel array of the template. The directional charge transport properties and high light harvesting capability of the CNA gives much better performance in splitting water to give hydrogen than its bulk counterpart.

Predictive value of early decreased plasma ghrelin level for three-month cognitive deterioration in patients with mild traumatic brain injury.

The orexigenic hormone, ghrelin, is tightly linked to cognition impairment in neurodegenerative disorders. No previous studies have investigated the early ghrelin concentration change in patients with mild traumatic brain injury (mTBI) and it's relationship to cognitive deterioration. This study was performed to investigate the early plasma ghrelin concentrations in patients with mTBI and to explore the relationship between ghrelin and cognitive deterioration.

Highly electrocatalytic activity of RuO₂ nanocrystals for triiodide reduction in dye-sensitized solar cells.

Dye-sensitized solar cells (DSCs) are promising alternatives to conventional silicon devices because of their simple fabrication procedure, low cost, and high efficiency. Platinum is generally used as a superior counter electrode (CE) material, but the disadvantages such as high cost and low abundance greatly restrict the large-scale application of DSCs. An efficient and sustainable way to overcome the limited supply of Pt is the development of high-efficiency Pt-free CE materials, which should possess both high electrical conductivity and superior electrocatalytic activity simultaneously.

Cu-Cu2O-TiO2 nanojunction systems with an unusual electron-hole transportation pathway and enhanced photocatalytic properties.

Multicomponent Cu-Cu2O-TiO2 nanojunction systems were successfully synthesized by a mild chemical process, and their structure and composition were thoroughly analyzed by X-ray diffraction, transmission electron microscopy, field-emission scanning electron microscopy, and X-ray photoelectron spectroscopy. The as-prepared Cu-Cu2O-TiO2 (3 and 9 h) nanojunctions demonstrated higher photocatalytic activities under UV/Vis light irradiation in the process of the degradation of organic compounds than those of the Cu-Cu2O, Cu-TiO2, and Cu2O-TiO2 starting materials. Moreover, time-resolved photoluminescence spectra demonstrated that the quenching times of electrons and holes in Cu-Cu2O-TiO2 (3 h) is higher than that of Cu-Cu2O-TiO2 (9 h); this leads to a better photocatalytic performance of Cu-Cu2O-TiO2 (3 h).

Disordered Co1.28Mn1.71O4 as a visible-light-responsive photocatalyst for hydrogen evolution.

Catching the sunlight: The disordered Co1.28Mn1.71O4 was synthesized by a facile reduction method in the presence of amorphous MnO2 precursors and Co(2+).