Background: There are conflicting data about the role of Leiden mutation in the pathogenesis of cerebral arterial thrombosis. In order to obtain relevant data, authors investigated the prevalence of factor V Leiden (A506G) both in healthy subjects and in a subgroup of ischaemic stroke patients.
Material And Methods: Blood samples of 171 healthy persons and 254 ischaemic stroke patients were examined by PCR method for Leiden mutation.