BioArena system for knowing and understanding the biological world: a review with new experimental results.

A simple observation is the basis of the development of BioArena system: according to the first observations during the biological incubation after inoculation there is formaldehyde (HCHO) emission from the chromatographic spots; in this emission process, the level of HCHO molecules decreases time dependently. In fact, the antibiotic effect of an antibiotic-like compound decreases in parallel with the HCHO emission. The investigations demonstrated clearly a unique function and role of endogenous HCHO and its one main reaction product, ozone (O3), in the antiproliferative (e.

Multiple beneficial effects of resveratrol and their chemical-biochemical basis.

On the basis of in vitro and in vivo investigations trans-resveratrol (RV) is a natural, concentration-dependent formaldehyde (HCHO) mobilizer, scavenger, capture and carrier molecule. The capturing and mobilization of HCHO from a given biological unit (e.g.

[Role of formaldehyde and its reaction products in mechanism of action of some plant ingredients].

BioArena as a complex bioautographic system was successfully used for studying mechanism of action of some characteristic plant ingredients (e.g., 1'-methyl-ascorbigen, trans-resveratrol, salicylic acid, cinnamic acid).