Publications by authors named "Zsombor Csoban"
Article Synopsis
- Batches of lactose tablets were created with varying initial tensile strengths and evaluated over 24 hours for changes in mechanical and physical properties after a thermal treatment at 100°C.
- Caffeine gastroresistant pellets were produced through drug layering and film coating, and their characteristics like shape, size, and dissolution profile were analyzed.
- A comparison of pellet-containing tablets with different pellet-filler ratios was conducted, revealing that thermal exposure enhanced mechanical properties without significantly affecting drug release.
The use of multiparticulate drug delivery systems can contribute to more efficient and safe therapy while stability and incompatibility problems can be avoided as well. The aim of the present work was to review the possible ways of production of pellets containing multiparticulate units and studying the most important factors influencing the product quality attributes after tablet compression. The relationship between the formulation variables (compression pressures, different amounts of tableting excipients) and the dissolution profile of the gastroresistant coated beads were investigated.
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