Anxiety levels among school-going adolescents in peri-urban areas of Karachi, Pakistan.

Introduction: Mental health problems are pervasive nowadays. Adolescents are often expected to balance academic performance with familial obligations and work to support the family financially if they belong to low-socio-economic areas. These pressures can lead to Anxiety, stress, and even depression.

Is a sedentary lifestyle a leading causal factor of obesity and distress in type 2 diabetes? A cross-sectional study in low-socioeconomic areas of Karachi, Pakistan.

Background: Worldwide, the burden of diabetes with obesity as comorbidity has intensely increased. Even though sedentary behaviour is not favourable for a healthy lifestyle, some people still live a sedentary lifestyle. There is a dire need to report cases of sedentary behaviour in people with diabetes and obesity in the slums of Karachi, Pakistan.

The Protective Effects of AT2R Agonist, CGP42112A, Against Angiotensin II-Induced Oxidative Stress and Inflammatory Response in Astrocytes: Role of AT2R/PP2A/NFκB/ROS Signaling.

Angiotensin II receptor type 2 (AT2R) agonists have been known to promote neuroprotection by limiting ischemic insult, neuronal proliferation, and differentiation. Further, AT2R agonists have also been associated with the suppression of neuroinflammation and neurodegeneration. Of note, brain astrocytes play a critical role in these neuroinflammatory and neurodegenerative processes.