Publications by authors named "Zoujun Peng"

Article Synopsis
  • A new portable swab that connects to smartphones has been developed to measure glucose (Glu) levels in food, which is crucial for diabetics.
  • The swab uses a combination of natural enzymes and nanozymes to efficiently detect Glu through a color change and fluorescence, making it easy to read the results.
  • Testing showed that this dual-mode detection method is effective for guiding diabetics in managing their glucose intake accurately.
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  • The study compares enzyme methods (using a CaF/MnO nanocomposite with dual activity) and nonenzyme methods for detecting uric acid (UA) in human serum, highlighting a long-standing debate in nanosensing.
  • The enzyme method uses uricase to produce reactive oxygen species (ROS) that oxidize a dye, while the nonenzyme method relies on UA's scavenging effect on ROS to measure UA levels.
  • Results show that the enzyme method offers better selectivity, and both methods effectively determine UA concentration, potentially improving detection accuracy when used together and supporting future design of nanozyme catalysts for biochemical applications.
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Nitrite is a typical food additive and preservative used in the food industry, which has attracted considerable attention due to its severe adverse effects on human health. Herein, a sensitive and highly selective ratiometric colorimetric sensing platform for the detection of nitrite was created based on a polymetallic oxide nanozyme, CoMnO nanofibers (CMO) catalysis integrated with the particular diazotization reaction. The nanozyme has superior oxidase-like activity ( was 0.

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Article Synopsis
  • Single-atom catalysts (SACs) are gaining attention for their high catalytic activity, but enhancing the atomic loading of metal atoms remains a challenge.
  • * The study introduces a new type of catalyst called iron and molybdenum co-doped dual single-atom catalysts (Fe/Mo DSACs), which showed improved atomic loading and strong oxidase-like and peroxidase-like activities.
  • * These Fe/Mo DSACs can effectively catalyze reactions that lead to a visible color change in a solution, providing a sensitive detection method for hydrogen peroxide and uric acid with significant improvements in catalytic efficiency compared to individual metal SACs.
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Organophosphorus pesticides (OPs) are widely used in agricultural production, but their residues could cause pollution to the environment and living organisms. In this paper, a simple dual-readout method for OPs detection was proposed based on ChOx single enzyme inhibition. Firstly, ChOx can catalyze the production of HO from choline chloride (Ch-Cl).

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  • A novel fluorescent method was developed using sulfate-loaded iron-nitrogen co-doped carbon quantum dots (SO-CQDs), created through an eco-friendly pyrolysis process using persimmon frost as a carbon source.
  • SO-CQDs showed excellent biocompatibility in SMMC-7721 cells, with over 95% cell viability after 24 hours of incubation, and they emitted bright blue fluorescence when excited at 365 nm, demonstrating good cell permeability.
  • The method effectively detects glyphosate by monitoring pH changes through the fluorescence variations of SO-CQDs, achieving a limit of detection of 0.066 ng/mL, and it has been successfully applied for analyzing glyphosate residues in food products
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In this study, we have developed a sensitive approach to measure organophosphorus pesticides (OPs) using graphitic-phase CN nanosheets (g-CN) combined with a nanomaterial-based quencher, MnO nanosheets (MnO NS). Since MnO NS can quench the fluorescence of g-CN via the inner-filter effect (IFE), enzymatic hydrolysate (thiocholine, TCh) can efficiently trigger the decomposition of MnO nanosheets in the presence of acetylcholinesterase (AChE) and acetylthiocholine (ATCh), resulting in the fluorescence recovery of g-CN. OPs, as inhibitors to AChE activity, can prevent the generation of TCh and decomposition of MnO nanosheets while exhibiting fluorescence quenching.

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A colorimetric gold nanoparticles (AuNPs)-based acetylcholinesterase (AChE) assay was designed for the first time to measure the concentration of parathion-methyl (PM) in lake water samples. In this assay, the analyte PM inhibited the hydrolysis of acetylthiocholine (ATCh) by AChE, preventing the formation of thiocholine (TCh) that would otherwise react with the AuNPs catalyst and deactivate the catalyst. Therefore, in the presence of PM, the AuNPs catalyzed the oxidation of the 3,3',5,5'-tetramethylbenzidine (TMB) colorimetric indicator to oxTMB, inducing a visual color change from colorless to blue.

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In this paper, a novel fluorescence assay has been constructed for the determination of parathion-methyl (PM) by using 4-amino-3-hydroxy-1-naphthalenesulfonic acid (AHNSA) as probe. MnO nanosheets (MnO NS) could quench the fluorescence of AHNSA, while Mn, the reduction product of MnO NS, has no influence on it, resulting in fluorescence recovery. This is because that MnO NS have oxidized characteristic, and they can react with choline (TCh), which is the product of acetylthiocholine (ATCh) catalyzed by acetylcholinesterase (AChE).

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