Chemical composition, acute toxicity, antioxidant and anti-inflammatory activities of Moroccan L.

Hydro-distilled essential oil (EO) from the leaves of the western Mediterranean and Moroccan endemic plant was analyzed by GC/MS and examined for its acute toxicity on mice, in order to establish the safe doses. Furthermore, the anti-Inflammatory activity was evaluated based on carrageenan and trauma induced rats paw edema and the antioxidant potential has been investigated using different methods including DPPH radical-scavenging assay, Trolox equivalent antioxidant capacity (TEAC) and Ferric-reducing antioxidant power assay (FRAP). The major identified compounds in GC/MS analysis were bornyl acetate (26.

Evaluation of anxiolytic activity of methanolic extract of Urtica urens in a mice model.

Background: The present study was designed to study anxiolytic property of methanolic extracts of Urtica urens; an important and commonly used for its medicinal properties belongs to urticaceae family.

Methods: The anxiolytic activity was evaluated with the adult mice by hole board test, and the light-dark box test, and motor coordination with the rota rod test. The efficacy of the plant extract (100-400 mg/kg) was compared with the standard anxiolytic drug diazepam (1 mg/kg i.