The Use of D-Optimal Mixture Design in Optimizing Formulation of a Nutraceutical Hard Candy.

The aim of this study was to optimize the formulation of hard candy with antiviral herbal extracts and flowered with peel essential oils. To substitute water fraction, the D-optimal mixture design was used. The optimized mixture fractions of the best hard candy formulation contain extract (10%), Asso extract (3.

Anti-obesity, anti-hyperglycaemic, anti-antipyretic and analgesic activities of extracts.

Objectives: The aim of this study is to evaluate the anti-obesity, anti-hyperglycaemic, analgesic and antipyretic activities of (GA).

Materials And Methods: GA methanol and water extracts (GAME, GAWE) were administered to high-fat-high-glucose diet (HFFD) rats.

Results: This study showed that GAME exhibited the highest antioxidant, anti-α-amylase and anti-lipase activities, with half inhibitory concentration (IC50) values 0.