Optimizing tacrolimus therapeutic drug monitoring in Tunisian kidney transplant recipients: exploring the variability in bioavailability and the correlation between pharmacokinetic parameters.

Objectives: While the existing literature extensively covers the topic of tacrolimus variability, it remains crucial to gather data that are tailored to the Tunisian population. Our primary goal was to assess the variability in tacrolimus bioavailability using the Cp(0)/weight dosage ratio in Tunisian kidney transplant patients. We also aimed to determine the correlations between blood trough level (Cp(0)) and the area under the concentration-time curve (AUC0-12 h) in this cohort.

Cultural, social, and economic influences on academic field choice among Jewish and Muslim students.

This study investigated the complex cultural, social, and economic factors influencing the choice of academic field among Jewish and Muslim students in Israeli higher education. By employing a mixed-methods approach, combining quantitative surveys and conjoint analysis, this research revealed significant differences between the two groups. Our findings indicate that Muslim students exhibit significantly higher levels of individualism compared to Jewish students, as measured by the individualism scale.

Investigating the Impact of Time of Day on Glycaemia in Response to Postprandial Supramaximal Sprints in Adults With Type 1.

Objectives: In this study, we explore the impact of postprandial exercise timing (morning vs evening) on glycemia in individuals with type 1 diabetes (T1D) during short all-out sprints on a cycle ergometer.

Methods: Ten healthy, physically sedentary male (n=7) and female (n=3) volunteers with T1D, 22.8±2.

Manganese dioxide-coated biocarbon for integrated adsorption-photocatalytic degradation of formaldehyde in indoor conditions.

Formaldehyde is a common indoor air pollutant with hazardous effects on human health. This study investigated the efficiency of biocarbon (BC) functionalized with variable contents of MnO for formaldehyde removal in ambient conditions via integrated adsorption-photocatalytic degradation technology. The sample with the highest formaldehyde removal potential was used to prepare a functional coating made of acrylic binder mixed with 20 wt% of the particles and applied on beech ( L) substrate.

Ultrasound Assessment in Children With Suspected Appendicitis: Time to Revise Diagnostic Criteria: A Prospective Cohort Study.

Although ultrasound is considered the gold standard for the evaluation of children with suspected appendicitis, there is still much debate about the most accurate ultrasound findings. The purpose of this study was to define the best ultrasound signs that could ultimately improve the diagnostic accuracy of ultrasound for diagnosing pediatric acute appendicitis, and to differentiate between simple appendicitis and complicated appendicitis. After approval by our Institutional Review Board, a prospective study was carried out from January 1, 2022, to July 31, 2023, in a pediatric emergency department.

MRI contribution in minimally displaced lateral humerus condylar fractures in children.

Introduction: Diagnosis and treatment of displaced humerus lateral condylar fracture is well codified with open reduction and pinning. For non-displaced or minimally displaced lateral condylar (NMDLC) fractures, diagnosis can be challenging because of cartilaginous structures none visualized on radiographs.

Aim: To determine the usefulness of MRI in evaluating articular extension of NMDLC fracture.

Predictive Factors of Acute Appendicitis in Children With Non-Visualized Appendix on Ultrasound: A Prospective Cohort Study.

Most studies have demonstrated the high accuracy of ultrasound for the diagnosis of acute appendicitis (AA) in children. However, the lack of visualization of the appendix on ultrasound is usually a challenge. The aim of this study was to identify any factors that might help the physician make the right decision when dealing with a child with suspected appendicitis and an appendix not seen on ultrasound.