Hepatitis B virus-associated nephropathy in a patient with diabetes mellitus.

Hepatitis B virus (HBV)-associated nephropathy is not a rare manifestation of HBV infection; this could result in diagnostic confusion and the possible misidentification of a diabetic patient with albuminuria. We present the first published case of a HBV-associated nephropathy occurring in a patient with diabetes. The patient was a 24-year-old man who was admitted to hospital with 4 days of generalized swelling and oliguria.

[Effect of coicis semen oil on renal interstitial fibrosis in rats with unilateral urethral obstruction].

Objective: To study the effect and mechanism of Coicis Semen oil (Kanglaite injection, KLT) on renal interstitial fibrosis induced by unilateral ureteral obstruction (UUO).

Method: Fifty-four male SD rats were randomly divided into 3 groups, 6 in each group, the sham operated group, the model group, and the KLT group. Renal interstitial fibrosis model was established in rats by UUO.

Association of uteroglobin G38A polymorphism with IgA nephropathy: a meta-analysis.

Both uteroglobin knockout and antisense transgenic mice develop pathological and clinical features similar to immunoglobulin A (IgA) nephropathy. However, several association studies of uteroglobin G38A polymorphism and IgA nephropathy showed controversial findings. We used meta-analysis to assess the impact of the uteroglobin G38A polymorphism on susceptibility to and progression of IgA nephropathy.

[The effect of kanglaite injection(KLT) on the proliferation and telomerase activity of rat mesangial cells].

Objective: To observe the effect of Kanglaite injection(KLT) on the proliferation and telomerase activity of mesangial cells in rats.

Method: MTT, telomere repeat amplification protocal (TRAP), ELISA, PAGE and silver-stain were applied to detect the growth rate and telomerase activity of MC after stimulation of KLT and IL-1.

Result: The growth rate of MC was enhanced by IL-1 stimulation, which was accompanied with a redection of the activity of telomerase.