Deep Underwater Image Quality Assessment With Explicit Degradation Awareness Embedding.

Underwater Image Quality Assessment (UIQA) is currently an area of intensive research interest. Existing deep learning-based UIQA models always learn a deep neural network to directly map the input degraded underwater image into a final quality score via end-to-end training. However, a wide variety of image contents or distortion types may correspond to the same quality score, making it challenging to train such a deep model merely with a single subjective quality score as supervision.

High-Precision Dichotomous Image Segmentation With Frequency and Scale Awareness.

Dichotomous image segmentation (DIS) with rich fine-grained details within a single image is a challenging task. Despite the plausible results achieved by deep learning-based methods, most of them fail to segment generic objects when the boundary is cluttered with the background. In fact, the gradual decrease in feature map resolution during the encoding stage and the misleading texture clue may be the main issues.

HiDAnet: RGB-D Salient Object Detection via Hierarchical Depth Awareness.

RGB-D saliency detection aims to fuse multi-modal cues to accurately localize salient regions. Existing works often adopt attention modules for feature modeling, with few methods explicitly leveraging fine-grained details to merge with semantic cues. Thus, despite the auxiliary depth information, it is still challenging for existing models to distinguish objects with similar appearances but at distinct camera distances.

Designed nucleus penetrating thymine-capped dendrimers: a potential vehicle for intramuscular gene transfection.

A nucleus penetrating vehicle is indispensible when seeking to deliver plasmid DNA for gene transfection. In this study, dendrimers with terminal thymine groups were synthesized to meet this objective. Through modifications of the hydrophilic and neutral thymine moieties on hyperbranched peripheries, these dendrimers can achieve biosafety, efficient endosomal escape ability, cytosolic accessibility, and eventually, nuclear entry for the purposes of gene transfection.

Stabilizing oil-in-water emulsions with regenerated chitin nanofibers.

Natural chitin is a highly crystalline biopolymer with poor aqueous solubility. Thus direct application of chitin is rather limited unless chemical modifications are made to improve its solubility in aqueous media. Through a simple dissolution and regeneration process, we have successfully prepared chitin nanofibers with diameters around 50nm, which form a stable suspension at concentrations higher than 0.

Self-assembled nanostructured cellulose prepared by a dissolution and regeneration process using phosphoric acid as a solvent.

This report describes a "green" method for preparing self-assembled nanostructured cellulose through a dissolution and regeneration process. Cold phosphoric acid is used to dissolve cellulose in order to convert crystalline cellulose into its molecular form. Self-assembly of cellulose molecules into nanostructured cellulose is achieved by using water to regenerate cellulose.

Co-caged gold nanoclusters and methyl motifs lead to detoxification of dendrimers and allow cytosolic access for siRNA transfection.

Nonviral vectors used in gene delivery, such as cationic polymers and dendrimers, exhibit problems of inherent toxicity and inefficient cytosolic access that must be overcome. In this work, a simple co-caging strategy focused on overcoming the two limitations of dendrimers for siRNA transfection is reported. By embedding gold nanoclusters within a dendrimer, the structure of the dendrimer becomes compact and allows an irreversible backfolding of exterior primary amines from the branch to the core, which dramatically eliminates dendrimer toxicity and enhances safety.

Recent progress in copolymer-mediated siRNA delivery.

RNAi-mediated gene silencing has great potential for treating various diseases, including cancer, by delivering a specific short interfering RNA (siRNA) to knock down pathogenic mRNAs and suppress protein translation. Although many researchers are dedicated to devising polymer-based vehicles for exogenous in vitro siRNA transfection, few synthetic vehicles are feasible in vivo. Recent studies have presented copolymer-based vectors that are minimally immunogenic and facilitate highly efficient internalizing of exogenous siRNA, compared with homopolymer-based vectors.

5,5'-Bis[(2,2,2-trifluoro-eth-oxy)meth-yl]-2,2'-bipyridine.

The complete molecule of the title compound, C(16)H(14)F(6)N(2)O(2), is generated by crystallographic inversion symmetry, which results in two short intramolecular C-H⋯N hydrogen-bond contacts per molecule. In the crystal, aromatic π-π stacking [centroid-centroid distance = 3.457 (2) Å] and weak C-H⋯π inter-actions occur.

4,4'-Bis(2,2,2-trifluoroethoxymethyl)-2,2'-bipyridine.

As part of a homologous series of novel polyfluorinated bipyridyl (bpy) ligands, the title compound, C(16)H(14)F(6)N(2)O(2), contains the smallest fluorinated group, viz. CF(3). The molecule resides on a crystallographic inversion centre at the mid-point of the pyridine C(ipso)-C(ipso) bond.