Synopsis of recent research by authors named "Zongwan Mao"
- Zongwan Mao's recent research focuses on novel metal complex compounds that trigger ferroptosis, enhance anti-tumor immunity, and address challenges in drug resistance in cancer therapy, as demonstrated in studies involving ruthenium and iridium complexes.
- His work also explores the mechanisms of action of bioactive compounds, such as the role of ATP synthase as a target for ruthenium complexes and the signaling pathways activated by these compounds in combating cancer cell resilience and promoting cell death.
- Additionally, Mao investigates the development of probes for real-time monitoring of mitochondrial DNA and G-quadruplexes to gain insights into their roles in mitochondrial function and the potential for targeted chemotherapy and immunotherapy using platinum-based drugs.
