UHPLC-HRMS-based Multiomics to Explore the Potential Mechanisms and Biomarkers for Colorectal Cancer.

Background: Understanding the metabolic changes in colorectal cancer (CRC) and exploring potential diagnostic biomarkers is crucial for elucidating its pathogenesis and reducing mortality. Cancer cells are typically derived from cancer tissues and can be easily obtained and cultured. Systematic studies on CRC cells at different stages are still lacking.

UHPLC-HRMS-based serum untargeted lipidomics: Phosphatidylcholines and sphingomyelins are the main disturbed lipid markers to distinguish colorectal advanced adenoma from cancer.

Colorectal advanced adenoma (CAA) is a key precancerous lesion of colorectal cancer (CRC), and early diagnosis can lessen CRC morbidity and mortality. Although abnormal lipid metabolism is associated with the development of CRC, there are no studies on the biomarkers and mechanism of lipid metabolism linked to CAA carcinogenesis. Hence, we performed a lipidomics study of serum samples from 46 CAA, and 50 CRC patients by the ultra high-performance liquid chromatography tandem high resolution mass spectrometry (UHPLC-HRMS) in both electrospray ionization (ESI) modes.

Carbon sequestration characteristics of two plantation forest ecosystems with different lithologies of karst.

In karst regions, the majority of studies have focused on ecosystem carbon sequestration in the same lithology, but no studies in different lithologies. In this study, actual measurements were used to reveal carbon sequestration characteristics of two plantation forest ecosystems (Bodinieri cinnamon and Cupressus funebris) with different lithologies of karst. The results showed that the tree layer showed the highest vegetation biomass, carbon content, carbon density, and ratio of aboveground biomass to belowground biomass.

Correlation between Vegetation Structure and Species Diversity in Traditional Villages in Karst Topographic Regions of the Zunyi City, China.

Studying the relationship between vegetation structure and diversity is important in an area having karst topography and unique traditional customs. We selected a total of six traditional villages in Zunyi City, China, to collect vegetation data. Additionally, using one-way ANOVA and the Pearson correlation coefficient analytic method to analyze, the results showed that, overall, plant communities were mostly regularly distributed.

Serum Untargeted UHPLC-HRMS-Based Lipidomics to Discover the Potential Biomarker of Colorectal Advanced Adenoma.

Background: As a key precancerous lesion, colorectal advanced adenoma (CAA) is closely related to the occurrence and development of colorectal cancer (CRC). Effective identification of CAA-related biomarkers can prevent CRC morbidity and mortality. Lipids, as an important endogenous substance, have been proved to be involved in the occurrence and development of CRC.

[Construction of green space ecological network in Dongting Lake region with comprehensive evaluation method].

Green space ecological network is important for improving the fragmentation of regional ecological space, biodiversity loss, imbalance of supply and demand in ecosystem services, and ensuring regional ecology. With Dongting Lake region as an example, the ecological sources were evaluated and identified, and basic ecological resistance of grid element was calculated from the perspectives of comprehensive ecosystem service function evaluation, potential biodiversity comprehensive index evaluation and morphological spatial pattern analysis with the support of 3S technology. We corrected the basic ecological resistance by night light index, used the minimum cumulative resistance model to identify ecological corridors, and constructed a weighted evaluation model, eva-luated the degree of aggregation and dispersion of the sources, as well as the contribution of ecological connection of the corridors.

The characteristics of habitat, functional traits and medicinal components of Eucommia ulmoides from Guizhou.

To find out the genuine characteristics of Eucommia ulmoides produced in Guizhou.The habitat, functional characters and the content of medicinal components of Eucommia ulmoides in Guizhou were studied by using the method of sample survey combined with typical survey, related laboratory experiments and quantitative analysis. The results showed that the yield of Eucommia ulmoides plantation in Guizhou was divided into low altitude, low middle and high temperature rain slope latitude mixing, short sunshine hours type(A type), medium altitude, low longitude and latitude, high temperature rain, positive oblique steep slope, medium sunshine hours type (B type), middle altitude, low longitude and latitude, moderate high temperature rain, shady side and sunny side have gentle deflection steep slope, medium sunshine hours type (C type), High altitude, low longitude and latitude, low temperature moderate rain, positive gentle slope, long sunshine hours type (D type); Different types of Eucommia ulmoides plantation, Different habitat quality, B type is intensity karst rocky desertification habitat, A type is potential karst rocky desertification habitat, the C and D types are light and moderate rocky desertification areas, respectively, the species diversity of shrub layer in Eucommia ulmoides plantation was higher in D type and B type, A type and C type followed; There was no significant difference in root carbon content and leaf nitrogen content in 4 types of Eucommia ulmoides plantation, Among the four types of A, B, C, D, there were significant or extremely significant differences in other indexes of plant functional traits; Both genipinic acid and aucubin had the highest content of root bark, followed by trunk bark and lowest leaves, Chlorogenic acid is the opposite, The content of geniposide was higher in trunk bark and lower in root bark and leaves; Genipinic acid is higher in D type, Aucubin is higher in A and D type, Chlorogenic acid has higher leaves content in B type, Geniposide was the highest in trunk bark of D type; The element enrichment coefficient K and Mn leaves are the largest, the largest in trunk bark is Ca and Zn, Fe root bark is the largest; Effects of soil potassium, phosphorus, pH value and bulk weight on the functional traits of Eucommia ulmoides were significant.

Effects of water and fertilizer coupling on the physiological characteristics and growth of rabbiteye blueberry.

Understanding the impact of irrigation and fertilizer on rabbiteye blueberry (Vaccinium virgatum) physiology is necessary for its precision planting. Here, we applied varied irrigation and fertilizer under completely randomized experimental design to see its impact on the physiological characteristics and bush growth of rabbiteye blueberries. A comprehensive evaluation of the membership function was used to establish the best water-fertilizer coupling regimes.

The Diagnostic and Prognostic Value of miR-200c in Gastric Cancer: A Meta-Analysis.

Background: The role of miR-200c in gastric cancer remains controversial. This study is aimed at clarifying the diagnostic and prognostic value of miR-200c in gastric cancer through a meta-analysis.

Methods: A comprehensive literature search of PubMed, Embase, and Ovid library databases was conducted.

Correlation between rs738409 polymorphism and hepatocellular carcinoma: a meta-analysis of 10,330 subjects.

Purpose: The correlation between patatin-like phospholipase domain-containing protein 3 () rs738409 polymorphism and hepatocellular carcinoma was investigated by several pilot studies, but the results of these studies were controversial. Therefore, we performed this study to better assess the relationship between rs738409 polymorphism and the likelihood of hepatocellular carcinoma.

Methods: Eligible studies were searched in PubMed, Medline, EMBASE, and Web of Science.

Region-confined restoration method for motion-blurred star image of the star sensor under dynamic conditions.

Under dynamic conditions, the centroiding accuracy of the motion-blurred star image decreases and the number of identified stars reduces, which leads to the degradation of the attitude accuracy of the star sensor. To improve the attitude accuracy, a region-confined restoration method, which concentrates on the noise removal and signal to noise ratio (SNR) improvement of the motion-blurred star images, is proposed for the star sensor under dynamic conditions. A multi-seed-region growing technique with the kinematic recursive model for star image motion is given to find the star image regions and to remove the noise.

Attitude-correlated frames approach for a star sensor to improve attitude accuracy under highly dynamic conditions.

The attitude accuracy of a star sensor decreases rapidly when star images become motion-blurred under dynamic conditions. Existing techniques concentrate on a single frame of star images to solve this problem and improvements are obtained to a certain extent. An attitude-correlated frames (ACF) approach, which concentrates on the features of the attitude transforms of the adjacent star image frames, is proposed to improve upon the existing techniques.

High-precision rolling angle measurement for a three-dimensional collimator.

We propose a precise rolling angle measurement for a collimator to extend its application in 3D angular deformation measurement, with performance significantly superior to that of the traditional 2D technique. The rolling angle measurement is realized by taking full advantage of the point array image, which is projected in terms of the collimated beam. The measurement error is estimated according to the proposed algorithm.

An improved method for dynamic measurement of deflections of the vertical based on the maintenance of attitude reference.

A new method for dynamic measurement of deflections of the vertical (DOV) is proposed in this paper. The integration of an inertial navigation system (INS) and global navigation satellite system (GNSS) is constructed to measure the body's attitude with respect to the astronomical coordinates. Simultaneously, the attitude with respect to the geodetic coordinates is initially measured by a star sensor under quasi-static condition and then maintained by the laser gyroscope unit (LGU), which is composed of three gyroscopes in the INS, when the vehicle travels along survey lines.

[Changes of foliar delta13C value of Quercus fabric in different root underground habitat types in Karst area].

Selecting the dominant tree species Quercus fabric in three root underground habitat types (the dolomites of low oblique occurrence with multilayer space, middle oblique occurrence with multilayer space, and high oblique occurrence with multilayer space) in Karst area as test object, this paper studied the foliar delta13C value and its correlations with habitat soil conditions, and the plant water use efficiency. There existed remarkable differences in the foliar delta13C value of Q. fabric among the three habitat types, being decreased in the order of low oblique occurrence with multilayer space type (-26.

[Characteristics of soil microbial biomass carbon and soil water soluble organic carbon in the process of natural restoration of Karst forest].

By the method of taking space instead of time, an incubation test was conducted to study the characteristics of soil microbial biomass carbon and water soluble organic carbon in the process of natural restoration of Karst forest in Maolan Nature Reserve, Guizhou Province of Southwest China. The soil microbial biomass carbon content and soil basal respiration decreased with increasing soil depth but increased with the process of the natural restoration, soil microbial quotient increased with increasing soil depth and with the process of restoration, and soil water soluble organic carbon content decreased with increasing soil depth. In the process of the natural restoration, surface soil water soluble organic carbon content increased, while sublayer soil water soluble organic carbon content decreased after an initial increase.

[Characteristics of soil mineralizable carbon pool in natural restoration process of Karst forest vegetation].

By the method of taking space instead of time, an incubation test was conducted to study the characteristics of soil mineralizable carbon pool during the natural restoration of Karst forest vegetation in Maolan Nature Reserve, Guizhou Province of Southwest China. It was observed that the contents of soil total organic carbon (TOC) and mineralizable carbon (MC) as well as the carbon mineralization rate decreased with increasing soil depth but increased with the process of vegetation restoration. The amount of cumulative released carbon and the carbon release rate increased with the process of restoration, but the release rate decreased with increasing incubation time.